Drug Exchanges between the Blood and Vitreous

  • David M. Maurice


The vitreous body, corresponding in function to the space between the lens and the film of a camera, is very properly ignored by most sensible people. However, as a large unstirred fluid space contiguous with the retina it provides unusual opportunities for characterizing solute exchanges with the central nervous tissue and its vasculature and has attracted some attention from a limited number of investigators (1–10). Unfortunately, it is the nature of such a stagnant pool to provide excellent conditions for the growth of microorganisms whether introduced by trauma or the surgeon’s knife. These infections are particularly resistant to chemotherapy, and so the question of drug exchanges between the blood and the vitreous body is of considerable clinical importance.


Anterior Chamber Aqueous Humor Vitreous Humor Lipid Solubility Vitreous Body 
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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • David M. Maurice
    • 1
  1. 1.Division of OphthalmologyStanford UniversityStanfordUSA

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