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The Blood-Retinal Barriers pp 165–178Cite as

Drug Exchanges between the Blood and Vitreous

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Abstract

The vitreous body, corresponding in function to the space between the lens and the film of a camera, is very properly ignored by most sensible people. However, as a large unstirred fluid space contiguous with the retina it provides unusual opportunities for characterizing solute exchanges with the central nervous tissue and its vasculature and has attracted some attention from a limited number of investigators (1–10). Unfortunately, it is the nature of such a stagnant pool to provide excellent conditions for the growth of microorganisms whether introduced by trauma or the surgeon’s knife. These infections are particularly resistant to chemotherapy, and so the question of drug exchanges between the blood and the vitreous body is of considerable clinical importance.

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Author information

Authors and Affiliations

  1. Division of Ophthalmology, Stanford University, Stanford, California, USA

    David M. Maurice

Authors
  1. David M. Maurice
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Editor information

Editors and Affiliations

  1. Abraham Lincoln School of Medicine, University of Illinois College of Medicine, USA

    Jose G. Cunha-Vaz (Professor, Director, Professor and Chairman) (Professor, Director, Professor and Chairman)

  2. Retina Service, University of Illinois Eye and Ear Infirmary, Chicago, Illinois, USA

    Jose G. Cunha-Vaz (Professor, Director, Professor and Chairman) (Professor, Director, Professor and Chairman)

  3. Department of Opthalmology, University of Coimbra, Portugal

    Jose G. Cunha-Vaz (Professor, Director, Professor and Chairman) (Professor, Director, Professor and Chairman)

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© 1980 Springer Science+Business Media New York

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Maurice, D.M. (1980). Drug Exchanges between the Blood and Vitreous. In: Cunha-Vaz, J.G. (eds) The Blood-Retinal Barriers. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4655-6_8

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  • DOI: https://doi.org/10.1007/978-1-4757-4655-6_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-4657-0

  • Online ISBN: 978-1-4757-4655-6

  • eBook Packages: Springer Book Archive

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