Abstract
Alterations in the transport and in the levels and regional distribution of amino acids occur under a variety of conditions, including normal development. Since the levels, distribution, and movement of amino acids have important effects on brain metabolism, their changes would be reflected in altered metabolism. An understanding of control of amino acid transport is a goal toward which we have directed much of our research interest. The results obtained suggest that there is no single mechanism that regulates acid transport, but that there are many transport systems with different properties influenced by a number of factors.
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References
Shaw, R.K. and Heine, J.D. (1965) J. Neurochem.12:151–155
Himwich, W.A. and Agrawal, H.C. (1969) In: Handbook of Neurochemistry, Vol. I, Chapter 3, A. Lajtha, ed., pp. 33–52.
Battistin L. and Lajtha, A. (1970) J. Neurol. Sci. 10: 313–322.
Kandera, J., Levi, G., and Levi, A. (1968) Arch. Biochem. Biophys. 126: 249–260.
Oldendorf, W.H. and Szabo, J. (1976) Am. J. Physiol. 230: 94–98
Sershen, H. and Lajtha, A. (1979) J. Neurochem. 32: 719–726.
Emirbekov, E.Z., Sershen, H., and Lajtha A. (1977) Br. Res. 125: 187–191.
Sershen, H. and Lajtha, A. (1976) Exp. Neurology 53: 465–474.
Levi, G., Kandera, J, and Lajtha, A. (1967) Arch. Biochem. Biophys. 119: 303–311.
Lajtha, A. and Toth, J. (1973) Brain Research 55: 238–251.
Seta, K., Sershen, H. and Lajtha, A. (1972) Brain Research 47: 415–425.
Sershen, H. and Lajtha, A. (1976) Neurochem. Res. 1: 417–428.
Piccoli, F., Grynbaum, A., and Lajtha, A. (1971) J. Neurochem. 18: 1135–1148.
Schultz, S.G. and Curran, P.F. (1970) Physiol. Rev. 50: 637–718.
Margolis, R.K. and Lajtha, A. (1968) Biochim. Biophys. Acta 163: 374–385.
Lahiri, S. and Lajtha, A. (1964) J. Neurochem. 11: 77–86.
Lajtha, A. and Sershen H. (1975) J. Neurochem. 24: 667–672.
Christensen, H.N. (1975) In: Current Topics in Membranes and Transport, F. Bronner and A. Kleinzeller, eds., Academic Press, N.Y., pp. 227–258.
Wade, L.A. and Kutzman, R. (1975) J. Neurochem. 25: 837–842.
Betz, A.L. and Goldstein, G.W. (1978) Science 202: 225–227.
Lajtha, A. and Sershen, H. (1975) Brain Research 84: 429–441.
Banay-Schwartz, M., Teller, D.N., Horn, B., and Lajtha, A. (1977) J. Neurochem. 29: 403–410.
Sershen, H. and Lajtha, A. (1974) J. Neurochem. 22: 977–985.
Banay-Schwartz, M., Gergely, A., and Lajtha, A. (1974) Brain Research 65: 265–276.
Logan, W.J. and Snyder, S.H. (1972) Brain Res. 42: 413–431.
Petersen, N.A. and Raghupathy, E. (1978) J. Neurochem. 31: 989–996.
Banay-Schwartz, M., Piro, L., and Lajtha, A. (1971) Arch. Biochem. 145:199–210.
Banay-Schwartz, M., Teller, D.N., Gergely, and Lajtha, A. (1974) Br. Res. 71: 117–131.
Teller, D.N., Banay-Schwartz, M., DeGuzman, T., and Lajtha, A. (1977) Brain Res. 131: 321–334.
Wexler, B. and Katzman, R. (1975) Exp. Cell Res. 92: 291–298.
Sparziani, E. (1975) Pharmac. Res. 27, 207–286.
Honoune, J., Chambaut, A.-M., Josipowicz, A. (1972) Arch, Biochem. Biophys. 148: 180–184.
Litteria, M. (1977) Exp. Neurol. 57: 817–827.
Litteria, M. (1977) Brain Res. 132: 287–289
Verity, M.A., Brown, Cheung, M.K., and Czer, G.T. (1977) J. Neurochem. 29: 853–858.
Young, D.A. (1969) J. Biol. Chem. 244: 2210–2217.
Sadasivada, B., Rao, I.T., and Krishna Murthy, R.C. (1977) Neurochem. Res. 3: 521–532.
Banay-Schwartz, M., Zanchin, G., DeGuzman, T,and Lajtha, A. (in press) Psychoneuroendocrinology
Wurtman, R.J. and Fernstrom, J.D. (1976) Biochem. Pharmacol. 25: 1691–1696.
Banay-Schwartz, M., Giuffrida, A.M., DeGuzman, T., Sershen, H., and Lajtha, A. (1979) Exp. Neurology 65: 157–168.
Enwonwu, C.O. and Worthington, B.S. (1974) J. Neurochem. 22: 1045–1052.
Toth, J. and Lajtha, A. (in preparation) The effect of protein-free diet on the uptake of amino acids by the brain in vivo.
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Lajtha, A., Sershen, H. (1980). Alterations of Amino Acid Transport in the Central Nervous System. In: Cunha-Vaz, J.G. (eds) The Blood-Retinal Barriers. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4655-6_6
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DOI: https://doi.org/10.1007/978-1-4757-4655-6_6
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