Intravascular Re-Targeting of Viral Vectors
In recent years, the concept of gene delivery has arisen as an alternative to more traditional drug delivery approaches. Although this concept was initially envisaged as a strategy to correct inherited genetic disorders, the approach has been substantially broadened to encompass the use of gene-based therapies for a variety of acquired diseases. In essence, the approach involves the delivery of nucleic acids (i.e. genes) into cells whereupon the host cell’s machinery will be used for transcription and translation, leading to in situ production of a protein which in turn will have an impact on cell function.
KeywordsGene Delivery Penton Base Biomedical Aspect Transductional Target Knob Domain
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