Abstract
Drugs face a formidable obstacle in reaching the central nervous systems (CNS) due to the existence and specific properties of the blood-brain barrier (BBB) that is a vital element in the regulation of the internal environment of the brain and the spinal cord. This chapter summarizes the principles and perspective of strategies that offer invasive and non-invasive approaches to overcome this major hurdle to the pharmacotherapy of the CNS.
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Prokai, L. (2002). Targeting Drugs into the Central Nervous System. In: Muzykantov, V., Torchilin, V. (eds) Biomedical Aspects of Drug Targeting. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4627-3_19
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DOI: https://doi.org/10.1007/978-1-4757-4627-3_19
Publisher Name: Springer, Boston, MA
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