Pulsatile Prosthetic Valve Flows: Laser-Doppler Studies

  • P. G. Alchas
  • A. J. Snyder
  • Winfred M. Phillips


Many of the factors related to cardiovascular disease seem to be significantly dependent upon the corresponding fluid dynamics of blood flow through the cardiovascular system. A knowledge of such fluid mechanical parameters as shear rate, turbulence intensities and recirculation areas in the entry region of the aorta, for example, would provide a better understanding of associated diseases (e.g., thrombus formation and endothelial damage). In addition, this knowledge would serve as a foundation for the design and testing of prosthetic heart valves.


Prosthetic Heart Valve Artificial Heart Aortic Prosthesis Prosthetic Aortic Valve Major Orifice 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Adams, P.M., “A Computer Graphics Simulation Technique and Related Results for Evaluating Blood Flow Characteristics through Prosthetic Heart Valves,” ISA BM Paper No. 75328, 1975.Google Scholar
  2. 2.
    Adrian, R.M. and Fingerson, L.M., “Laser Anemometry… Theory, Applications, and Techniques, TSI Short Course and Workshop, Boston, 1977.Google Scholar
  3. 3.
    Agrawal, Y.C., “Laser Velocimeter Study of Entrance Flows in Curved Pipes,” University of California, Berkeley, Rept. No. FM-75–1, Jan. 1975.Google Scholar
  4. 4.
    Bellhouse, B.J., “Velocity and Pressure Distributions in the Aortic Valve,” J. of Fluid Mechanics 37, pt. 3, 1969.Google Scholar
  5. 5.
    Bjork, Viking 0., “The Improved Bjork-Shiley Tilting Disc Valve Prosthesis,” presented at Pan Pacific Surgical Convention, April 7, 1978.Google Scholar
  6. 6.
    Figliola, R.S. and Mueller, T.J., “InVitro Measurements of Fluid Stresses in the Vicinity of a Disc-Type Prosthetic Heart Valve,” Proc. 29th ACEMB Conf., Boston, 1976.Google Scholar
  7. 7.
    Furkay, S.S., “Fluid Dynamics of the Bjork-Shiley Aortic Valve Prosthesis and PSU Prosthetic Ventricle,” M.S. Thesis, The Pennsylvania State University, August 1979.Google Scholar
  8. 8.
    George, W.K. and Lumley, J.L., “The Laser-Doppler Anemometer and Its Application to the Measurement of Turbulence, ” J. of Fluid Mechanics, Vol. 60, pt. 2, 1973.Google Scholar
  9. 9.
    Greenfield, H., Au, A., Kelsey, S., and Kolff, W., “Simulation of Assumed Detriments to Prosthetic Heart Function,” Trans. American Soc. for Art. Int. Organs, Vol. 20-B, 1974.Google Scholar
  10. 10.
    Hussain, A.K.M.F., “Mechanics of Pulsatile Flows of Relevance to the Cardiovascular System,” from Cardiovascular Flow Dynamics and Measurements, N.H.C. Hwang and N.A. Normann, editors, University Park Press, Baltimore, 1977.Google Scholar
  11. 11.
    Kreid, D.K. and Goldstein, R.J., “Measurement of Velocity Profiles in Simulated Blood by the Laser–Doppler Technique,” Proc. Symposium on Flow, Paper No. 4–2–95, Pittsburgh, May 10 – 12, 1971.Google Scholar
  12. 12.
    Lenker, J.A., “Flow Studies in Artificial Hearts and LVAD: An Application of Flow Visualization Analysis,” Ph.D. Dissertation, The Pennsylvania State University, 1978.Google Scholar
  13. 13.
    Ly, D.P. and Bousquet, A., “Determination of Velocity Profiles by Laser-Doppler Anemometry in Pulsating Laminar Flow of Non-Newtonian Fluids,” Proc. LDA-75 Symposium, Technical University ofDenmark, Copenhagen, 1975.Google Scholar
  14. 14.
    Modi, V.J. and Aminzadeh, M., “Fluid Mechanics of an Aortic Valve Implant,” Proc. ASME Biomechanics Symp., 1977.Google Scholar
  15. 15.
    Peronneau, P.A., Pellet, M.M., Xhaard, M.C. and Hingalis, J.R., “Pulsed Doppler Ultrasonic Blood Flowmeter Real–Time Instantaneous Velocity Profiles,” from Proc. Symp. on Flow, Theme IV: Biological Flows, Paper No. 4–2–146, Pittsburgh, May 10 – 12, 1971.Google Scholar
  16. 16.
    Peskin, C.S., “Flow Patterns Around Heart Valves: A Numerical Method,” J. of Computational Physics, Vol. 10, 1972.Google Scholar
  17. 17.
    Phillips, W.M., Lenker, J.A., Brighton, J.A. and Pierce, W.S., “Flow Visualization Methods for In Vitro Cardiovascular Flow Studies,” Proc. 29th Conf. on Eng. in Med. and Biol., Boston, 1976.Google Scholar
  18. 18.
    Pierce, W.S., “Development and Evaluation of Left Ventricular Assist and Artificial Heart,” NIH Contractor’s Report NO1-HV-3–2966, June 1974.Google Scholar
  19. 19.
    Rosenberg, G., “A Mock Circulatory System for In Vitro Studies of Artificial Hearts,” M.S. Thesis, The Pennsylvania State University, 1972.Google Scholar
  20. 20.
    Sabbah, H.N. and Stein, P.D., “Turbulent Blood Flow in Humans, ” Circulation Research, 38, No. 6, 1976.Google Scholar
  21. 21.
    Saklad, E. and Moskowitz, G., “Plane Flow Through a Prosthetic Aortic Valve,” Proc. 25th Conf. on Eng. in Med. and Biol. Bal Harbour, Florida, 1972.Google Scholar
  22. 22.
    Swope, R.D. and Falsetti, H.L., “Velocity Profiles in Prosthetic Heart Valves under Steady Flow Conditions,” Proc. 29th Conf. on Eng. in Med. and Biol., Boston, 1976.Google Scholar
  23. 23.
    Tennekes, H. and Lumley, J.L., A First Course in Turbulence, MIT Press, Cambridge, Mass., 1972.Google Scholar
  24. 24.
    Underwood, F.N. and Mueller, T.J., “Numerical Study of the Steady Axisymmetric Flow through a Disc-Type Prosthetic Heart Valve in a Constant Diameter Chamber,” J. Biomechanical Eng, Vol. 99 (2), 1977.Google Scholar
  25. 25.
    Yoganathan, A.P., Corcoran, W.H., Harrison, E.C. and Carl, J.R., “The Bjork-Shiley Aortic Prosthesis: Flow Characteristics, Thrombus Formation, and Tissue Overgrowth, ” Circulation 3 (1), 1978.Google Scholar

Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • P. G. Alchas
    • 1
  • A. J. Snyder
    • 1
  • Winfred M. Phillips
    • 1
  1. 1.Artificial Heart Engineering Laboratory 312 Mechanical Engineering Bldg.The Pennsylvania State Univ.Univ. ParkUSA

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