Collagen and Cell Differentiation

  • A. H. Reddi


Cell differentiation is one of the central problems of contemporary biology and medicine. How does the fertilized egg develop into an adult organism with a myriad of cell types? It is common knowledge that all cells in a multicellular organism possess the same genetic information, hence an identical genotype. What is the molecular basis of the progressive appearance of diverse phenotypes from cells with the same genotype? The alteration of gene expression during development is of cardinal importance in cell differentiation.


Heparan Sulfate Bone Matrix Collagen Synthesis Collagenous Matrix Calcify Cartilage 
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© Springer Science+Business Media New York 1976

Authors and Affiliations

  • A. H. Reddi
    • 1
  1. 1.The Ben May Laboratory for Cancer ResearchUniversity of ChicagoChicagoUSA

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