Immunological Studies on Collagen

  • Rupert Timpl


The first unequivocal evidence that collagen is an antigenic protein was provided by the work of Watson et al. (1954). Subsequent to that study there was a steadily increasing interest in this topic (for previous review articles, see Kirrane and Glynn, 1968; O’Dell, 1968). Later on, the rapid progress made on structural aspects of collagen provided the background for more sophisticated immunological approaches. Thus, to date collagen can be considered as a well-characterized protein antigen (Furthmayr and Timpl, 1976)


Antigenic Determinant Antigenic Site Immunological Study Human Collagen Denature Collagen 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Rupert Timpl
    • 1
  1. 1.Max-Planck-Institut für BiochemieMartinsried b. MünchenGermany

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