Abstract
The biosynthesis of collagen has many similarities to the biosynthesis of other proteins synthesized for “export,” but collagen biosynthesis is distinguished by at least two prominent features: (1) the protein is first synthesized as a precursor form which fulfills several important functions, and (2) the biosynthesis involves several unusual posttranslational modifications which occur after assembly of amino acids into the three polypeptide chains of the molecule and which are essential for some of its critical structural features.
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Prockop, D.J., Berg, R.A., Kivirikko, K.I., Uitto, J. (1976). Intracellular Steps in the Biosynthesis of Collagen. In: Ramachandran, G.N., Reddi, A.H. (eds) Biochemistry of Collagen. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4602-0_5
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