Mycobacterial Invasion of Epithelial Cells

  • Luiz E. Bermudez
  • Felix J. Sangari
Part of the Subcellular Biochemistry book series (SCBI, volume 33)


Infections caused by organisms of the genera mycobacteria are responsible for a great percentage of yearly deaths dues to infectious diseases. Tuberculosis is a widespread infection caused by Mycobacterium tuberculosis. It is transmitted mainly as an airborne infection. M. bovis is found in cattle and it is transmitted to humans via contaminated milk and dairy products. Infections caused by Mycobacterium avium complex can cause localized disease usually in patients with underlying lung disease as well as disseminated disease in individuals with immunosuppression or Acquired Immunodeficiency Syndrome (AIDS). According to the World Health Organization, infections caused by mycobacteria will rise to 12 million cases annually by the year 2000.


Intestinal Mucosa Intestinal Epithelial Cell Alveolar Epithelial Cell Mycobacterium Avium Mycobacterium Avium Complex 
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Copyright information

© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Luiz E. Bermudez
    • 1
  • Felix J. Sangari
    • 1
  1. 1.Kuzell Institute for Arthritis and Infectious DiseasesCalifornia Pacific Medical Center Research InstituteSan FranciscoUSA

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