Skip to main content

New Studies on the Circulatory Effects of Ergot Compounds with Implications to Migraine

  • Chapter

Abstract

Ergot alkaloids have come to assume a pivotal position in migraine therapy. Not only does this group include the most potent drugs for the relief of the acute attack, but it also provides the most effective prophylactic drugs available.

The paper is being reprinted with the permission of the International Symposium on Headache, October 1969, Chicago, USA.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Aellig, W. H. (1967). Periphere Kreislaufwirkungen von Ergotamin, Dihydroergotamin und 1-Methyl-ergotamin an der innervierten, perfundierten Hinterextremität des Hundes. Helv. physiol. pharmacol. Acta, 25, 374.

    Google Scholar 

  • Aellig, W. H. and Berde, B. (1969). Studies of the effect of natural and synthetic polypeptide type ergot compounds on a peripheral vascular bed. Brit. J. Pharmacol. 36, 561.

    Article  Google Scholar 

  • Cerletti, A. and Berde, B. (1969). New approaches in the development of compounds from ergot with potential therapeutic use in migraine. In Background to Migraine. London: William Heinemann Medical Books.

    Google Scholar 

  • Konzett, H. and Rothlin, E. (1953). Investigations on the hypotensive effect of the hydrogenated ergot alkaloids. Brit. J. Pharmacol. Chemother. 8, 201.

    Article  Google Scholar 

  • Pacha, W. and Salzmann, R. (1970). Inhibition of the re-uptake of neuronally liberated noradrenaline and α-adrenergic blocking action of some ergot alkaloids. Brit. J. Pharmacol. 38, 439.

    Google Scholar 

  • Rothlin, E. (1946/47). The pharmacology of the natural and dihydrogenated alkaloids of ergot. Bull. Schweiz. Akad. med. Wiss. 2, 249.

    Google Scholar 

  • Salzmann, R. and Pacha, W. (1968). Vergleichende Untersuchungen über die Beeinflussung adrenerger Reaktionen durch Ergotamin und Dihydroergotamin an verschiedenen Versuchsmodellen. Helv. physiol. pharmacol. Acta, 26, 246.

    Google Scholar 

  • Salzmann, R., Pacha, W. and Taeschler, M. et al. (1968). The effect of ergotamine on humoral and neuronal actions in the nictitating membrane and the spleen of the cat. Naunyn-Schmiedebergs Arch. Pharm. exp. Path. 261, 360.

    Article  Google Scholar 

  • Salzmann, R., Pacha, W. and Weidmann, H. (1967). Der Einfluss von Ergotamin auf humorale und neuronale Wirkungen an der Nickhaut und an der Milz der Katze. Helv. physiol. pharmacol. Acta, 25, 433.

    Google Scholar 

  • Thoenen, H., Hürlimann, A. and Haefely, W. (1963). The effect of post-ganglionic sympathetic Stimulation on the isolated, perfused spleen of the cat. Helv. physiol. pharmacol. Acta, 21, 17.

    Google Scholar 

  • Thoenen, H., Hürlimann, A. and Haefely, W. (1964). Dual site of action of phenyoxybenzamine in the cat’s spleen: blockade of α-adrenergic receptors and inhibition of re-uptake of neurally released norepinephrine. Experientia (Basel), 20, 272.

    Article  Google Scholar 

  • Udenfriend, S. (1964). Fluorescence Assay in Biology and Medicine, page 158. New York/London, Academic Press.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1971 Springer Science+Business Media New York

About this chapter

Cite this chapter

Berde, B. (1971). New Studies on the Circulatory Effects of Ergot Compounds with Implications to Migraine. In: Cumings, J.N. (eds) Background to Migraine. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4577-1_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-4577-1_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-4579-5

  • Online ISBN: 978-1-4757-4577-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics