Laboratory Assessment of Skeletal Status

  • Richard Eastell
  • Penny R. Bainbridge


Bone turnover markers have been used in medicine for over 70 years. They have proved indispensable in the management of metabolic bone diseases such as Paget’s disease of bone. The changes in bone turnover in osteoporosis are small; thus, markers that are not specific to bone were not very useful in investigating this disease. However, assays have recently been introduced that are more specific for bone. In this chapter, we consider the evidence for the use of these markers in the investigation of osteoporosis.


Bone Mineral Density Vertebral Fracture Bone Turnover Marker Bone Resorption Marker Secondary Osteoporosis 
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© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Richard Eastell
  • Penny R. Bainbridge

There are no affiliations available

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