Since the first human heart transplantation in 1967 , cardiac transplantation has evolved from a medical curiosity to an accepted therapy for end-stage cardiomyopathy. Initial 1-year survival was only about 20%. With the general availability of cyclosporine in 1986, 1-year survival improved to more than 80%, with current 1-year survival now approaching 90% at high-volume transplant centers. Accordingly, the number of transplantations increased worldwide from 90 in 1981 to 2000 in 1988 to 3122 in 2001 .
KeywordsHeart Transplantation Left Ventricular Assist Device Cardiac Transplantation Cardiac Allograft Vasculopathy Heart Lung Transplant
Unable to display preview. Download preview PDF.
- 1.Barnard CN: A human cardiac transplant: an interim report of a successful operation performed at Groote Schuur Hospital, Cape Town. S Afr Med J 1967, 41: 1271–1274.Google Scholar
- 11.Costanzo MR: Selection and treatment of candidates for heart transplantation: a statement for health professionals from the Committee on Heart Failure and Cardiac Transplantation of the Council on Clinical Cardiology, American Heart Association. Circulation 1995, 92: 3593–3612.PubMedCrossRefGoogle Scholar
- 16.Cooley DA: Techniques in Cardiac Surgery, edn 2. Philadelphia: WB Saunders; 1984: 372.Google Scholar
- 18.Cerilli GJ: Organ Transplantation and Replacement. Philadelphia: JB Lippincott; 1988.Google Scholar
- 19.Unverferth DV: Dilated Cardiomyopathy. Mt. Kisco, NY: Futura Publishing Co; 1985.Google Scholar
- 25.Costanzo-Nordin MR: Cardiac allograft vasculopathy: relationship with acute cellular rejection and histocompatibility. J Heart Lung Transplant 1992, 11 (suppl): 90–104.Google Scholar
- 26.Johnson MR: Transplant coronary artery disease: nonimmunologic risk factors. J Heart Lung Transplant 1992, 11 (suppl): 124–132.Google Scholar
- 30.Helman D, Morales D, Edwards N, et al.: Left ventricular assist device bridge-to-transplant network improves survival after failed cardiotomy. Ann Thorac Surg 1999, 68:1187–1194.Google Scholar
- 33.Sabbah H, Chaudhry P, Paone G, et al.: Passive ventricular constraint with the ACORN prosthetic jacket prevents progressive left ventricular dilation and improves ejection fraction in dogs with moderate heart failure. J Am Coll Cardiol 1999, 33: 207A.Google Scholar