Molecular and Cellular Basis of Contraction and Relaxation

  • Arnold M. Katz


The ability of the heart to meet the changing demands of the circulation involves three fundamentally different mechanisms. The work of the heart can be regulated by changes in its ability to empty and fill (organ physiology), to utilize chemical energy for the performance of mechanical and osmotic work (cell biochemistry), and to replace its constituent parts (gene expression). Each of these control mechanisms operates over a different time course.


Sarcoplasmic Reticulum Thin Filament Cellular Basis Thick Filament Sodium Pump 
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© Springer Science+Business Media New York 2005

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  • Arnold M. Katz

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