• Karen L. Fink
  • Elisabeth J. Rushing
  • S. Clifford ScholdJr.


The field of neuro-oncology is a relatively young one. Most of the advances in neurologic diagnosis and therapy relevant to neuro-oncology have occurred within the last 85 years. Before the development of theories of neurologic localization, the presence of a brain tumor could be suspected, but treatment was impossible. Once preoperative localization using clinical examination techniques was possible, surgery for diagnosis and treatment of brain tumors was an option, but successful brain tumor surgery required the development of aseptic surgical techniques, anesthetics, antibiotics, and corticosteroids. Nonsurgical treatments for brain tumors were also developed in the twentieth century, including radiotherapy and chemotherapy. Refinements of these treatments are still being developed, and include γ-knife radiosurgery, radiosensitizers, localized chemotherapy using polymer wafers, gene therapy, and multiagent chemotherapy regimens for specific brain tumors.


Brain Tumor Brain Metastasis Pituitary Adenoma Pilocytic Astrocytoma Primary Brain Tumor 
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© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Karen L. Fink
  • Elisabeth J. Rushing
  • S. Clifford ScholdJr.

There are no affiliations available

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