Neuromuscular Disease

  • David Pleasure
  • Shawn Bird
  • Steven Scherer
  • John Sladky
  • Donald Schotland


This chapter illustrates diseases that involve the peripheral nervous system and skeletal muscle. In such diseases, the history and physical examination frequently provide sufficient data to arrive at the correct diagnosis. For example, autonomic dysfunction, distal limb weakness, hyporeflexia, and sensory loss in an adult with long-standing diabetes mellitus are probably due to diabetic neuropathy, and fluctuating weakness of bulbar and ocular muscles without sensory or reflex alterations strongly suggests myasthenia gravis. The clinical diagnosis can often be validated by specific immunochemical, biochemical, or molecular blood tests (Fig. 11-1).


Duchenne Dystrophy Myotonic Dystrophy Compound Muscle Action Potential Chronic Inflammatory Demyelinating Polyneuropathy Onion Bulb 
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© Springer Science+Business Media New York 2003

Authors and Affiliations

  • David Pleasure
  • Shawn Bird
  • Steven Scherer
  • John Sladky
  • Donald Schotland

There are no affiliations available

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