Skip to main content
SpringerLink
Log in

AIDS-Associated Malignancies

  • Chapter
Atlas of AIDS

  • 103 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Rabkin CS, Janz S, Lash A, et al.: Monoclonal origin of multicentric Kaposi’s sarcoma lesions. N Engl J Med 1997, 336:988–993.

    Article  PubMed  CAS  Google Scholar 

  2. Moore PS, Chang Y: Kaposi’s sarcoma-associated herpesvirus-encoded oncogenes and oncogenesis. J Natl Cancer Inst Monogr 1998, 23:65–71.

    Article  PubMed  Google Scholar 

  3. Krown SE: Kaposi’s sarcoma. In Principles and Practice of the Biological Therapy of Cancer, edn 3. Edited by Rosenberg SA. Philadelphia: Lippincott Williams & Wilkins; 2000:256–275.

    Google Scholar 

  4. Krown SE: Diagnosis and treatment of AIDS-associated Kaposi’s sarcoma. In AIDS-related Cancers and Their Treatment Edited by Feigal EG, Levine AM, Biggar RJ. New York: Marcel Dekker; 2000:59–95.

    Google Scholar 

  5. Gill PS, Wernz J, Scadden DT, et al.: Randomized phase II trial of liposomal daunorubicin (DaunoXome) versus doxorubicin, bleomycin, vincristine (ABV) in AIDS-related Kaposi’s sarcoma. J Clin Oncol 1996, 14:2353–2364.

    PubMed  CAS  Google Scholar 

  6. Stewart S, Jablonowski H, Goebel FD, et al.: Randomized comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi’s sarcoma. International Pegylated Liposomal Doxorubicin Study Group. J Clin Oncoi 1998:683–691.

    Google Scholar 

  7. Northfelt DW, Dezube BJ, Thommes JA, et al.: Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi’s sarcoma: results of a randomized phase III clinical trial. J Clin Oncol 1998, 16:2445–2451.

    PubMed  CAS  Google Scholar 

  8. Welles L, Saville MW, Lietzau J, et al.: Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi’s sarcoma. J Clin Oncol 1998, 16:1112–1121.

    PubMed  CAS  Google Scholar 

  9. Gill PS, Tulpule A, Espina BM, et al.: Paclitaxel is safe and effective in the treatment of advanced AIDS-related Kaposi’s sarcoma. J Clin Oncol 1999, 17:1876–1883.

    PubMed  CAS  Google Scholar 

  10. Ho DD, Hartshorn KL, Rota TR, et al.: Recombinant human interferon alpha-A suppresses HTLV-III replication in vitro, Lancet 1985, 1:602–604.

    Article  CAS  Google Scholar 

  11. Tilg H, Mier JW, Vogel W, et al.: Induction of circulating IL-1 receptor antagonist by IFN treatment. J Immunol 1993, 150:4687–4692.

    PubMed  CAS  Google Scholar 

  12. Ezekowitz RAB, Mulliken JB, Folkman J: Interferon alfa-2a for life-threatening hemangiomas of infancy. N Engl J Med 1992, 326:1456–1463.

    Article  PubMed  CAS  Google Scholar 

  13. Krown SE, Myskowski PL, Paredes J: Kaposi’s sarcoma: Management of Kaposi’s sarcoma in HIV-infected patients. Med Clin North Am 1992, 76:235–252.

    PubMed  CAS  Google Scholar 

  14. Pitha P: Multiple effects of interferon on HIV-1 replication. J Interferon Res 1991, 11:313–318.

    Article  PubMed  CAS  Google Scholar 

  15. Hartshorn KL, Vogt MW, Chou TC, et al.: Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant inter-feron-alpha A. Antimicrob Agents Chemother 1987, 31:168–172.

    Article  PubMed  CAS  Google Scholar 

  16. Johnson VA, Merrill DP, Videler JA, et al.: Two-drug combinations of zidovudine, didanosine, and recombinant interferon-alpha A inhibit replication of zidovudine-resistant human immunodeficiency virus type 1 syner-gistically in vitro. J Infect Dis 1991, 164:646–655.

    Article  CAS  Google Scholar 

  17. Vogt MW, Durno AG, Chou TC, et al.: Synergistic interaction of 2’, 3’-dideoxycytidine (ddCyd) and recombinant interferon alpha A (rIFN-alpha A) on HIV-1 replication. J Infect Dis 1988, 158:378–385.

    Article  PubMed  CAS  Google Scholar 

  18. Scadden DT, Bering HA, Levine JD, et al.: Granulocyte-macrophage colony-stimulating factor mitigates the neutropenia of combined interferon alfa and zidovudine treatment of acquired immune deficiency syndrome-associated Kaposi’s sarcoma. J Clin Oncol 1991, 9:802–808.

    PubMed  CAS  Google Scholar 

  19. Krown SE, Paredes J, Bundow D, et al.: Interferon-alpha, zidovudine, and granulocyte-macrophage colony-stimulating factor: A phase I AIDS Clinical Trials Group study in patients with Kaposi’s sarcoma associated with AIDS. J Clin Oncol 1992, 10:1344–1351.

    PubMed  CAS  Google Scholar 

  20. Krown SE, Li P, VonRoenn J, Testa M: Multicenter, randomized, open-label, phase II trial of two doses of interferon (IFN)-α2b with didanosine (ddI) in HIV-related Kaposi’s sarcoma: ACTG 206 [abstract]. J Acquir Immune Defic Syndr Human Retrovir 2000, 23:A22.

    Google Scholar 

  21. Jones JL, Hanson DL, Chu SY, et al.: AIDS-associated Kaposi’s sarcoma [letter]. Science 1995, 267:1078–1079.

    Article  PubMed  CAS  Google Scholar 

  22. Mocroft A, Youle M, Gazzard B, et al.: Anti-herpesvirus treatment and risk of Kaposi’s sarcoma in HIV infection. Royal Free/Chelsea and Westminster Hospitals collaborative group. AIDS 1996, 10:1101–1105.

    Article  PubMed  CAS  Google Scholar 

  23. Knowles DM, Inghirami G, Ubriaco A, et al.: Molecular genetic analysis of three AIDS-associated neoplasms of uncertain lineage demonstrates their B-cell derivation and the possible pathogenetic role of the Epstein-Barr virus. Blood 1989, 73:792–799.

    PubMed  CAS  Google Scholar 

  24. Ballerini P, Gaidano G, Gong JZ, et al.: Multiple genetic lesions in AIDS-related non-Hodgkin lymphoma. Blood 1993, 81:166–176.

    PubMed  CAS  Google Scholar 

  25. Kaplan LD, Straus DJ, Testa MA, et al.: Low-dose compared with standard-dose m-BACOD chemotherapy for non-Hodgkins’s lymphoma associated with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group. N Engl J Med 1997, 336(23)1641–1648.

    Article  PubMed  CAS  Google Scholar 

  26. Straus DJ, Huang J, Testa MAet al.: Prognostic factors in the treatment of human immunodeficiency virus-associated non-Hodgkin’s lymphoma: analysis of AIDS Clinical Trials Group protocol 142-low dose versus standard dose m-BACOD plus granulocyte-macrophage colony-stimulating factor. National Institute of Allergy and Infectious Diseases. J Clin Oncol 1998, 16:3601–3606.

    PubMed  CAS  Google Scholar 

  27. Scadden DT. Non-Hodgkin’s lymphoma: future targets for prevention and therapy. In AIDS-related Cancers and Their Treatment. Edited by Feigal EG, Levine AM, Biggar RJ. New York: Marcel Dekker; 2000:195–207.

    Google Scholar 

  28. Baumgartner JE, Rachlin JR, Beckstead JH, et al.: Primary central nervous system lymphoma: Natural history and response to radiation therapy in 55 patients with acquired immunodeficiency syndrome. J Neurosurg 1990, 73:206–211.

    Article  PubMed  CAS  Google Scholar 

  29. Nisce LZ, Metroka C: Radiation therapy in patients with AIDS-related central nervous system lymphoma. JAMA 1992, 267:1921–1922.

    Article  PubMed  CAS  Google Scholar 

  30. Forsyth PA, Yahalom J, DeAngelis LM, et al.: Combined-modality therapy in the treatment of primary central nervous system lymphoma in AIDS. Neurology 1994, 44:1473–1479.

    Article  PubMed  CAS  Google Scholar 

  31. Werness BA, Levine AJ, Howley PM: Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 1990, 248:76–79.

    Article  PubMed  CAS  Google Scholar 

  32. Dyson N, Howley PM, Munger K, et al.: The human papilloma virus-16 E7 oncoprotein is able to bind the retinoblastoma gene product. Science 1989,243:934–937.

    Article  PubMed  CAS  Google Scholar 

  33. Maiman M, Fruchter RG, Guy L, et al.: Human immunodeficiency virus infection and invasive cervical carcinoma. Cancer 1993, 71:402–406.

    Article  PubMed  CAS  Google Scholar 

  34. Lorenz HP, Wilson W, Leigh B, et al.: Squamous cell carcinoma of the anus and HIV infection. Dis Colon Rectum 1991, 34:336–338.

    Article  PubMed  CAS  Google Scholar 

  35. Rabkin CS, Biggar RJ, Horn J: Cancer trends associated with increasing AIDS. In the Proceedings of the VI International Conference on AIDS, San Francisco, 1990, 1:295.

    Google Scholar 

  36. Svensson C, Kaigas M, Lindbrink E, et al.: Carcinoma of the anal canal in a patient with AIDS. Acta Oncol 1991, 30:8986–8991.

    Article  Google Scholar 

  37. Maiman M, Tarricons N, Viera J, et al.: Colposcopic evaluation of human immunodeficiency virus seropositive women. Obstet Gynecol 1991, 78:84–88.

    PubMed  CAS  Google Scholar 

Selected Bibliography

  • Feigal EG, Levine AM, Biggar RJ: AIDS-related Cancers and Their Treatment. New York: Marcel Dekker; 2000.

    Google Scholar 

Download references

Authors
  1. Susan E. Krown
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Josephine Paredes
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Division of Infectious Diseases, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA

    Gerald L. Mandell MD (Professor of Medicine, Owen R. Cheatham Professor of the Sciences, Chief) (Professor of Medicine, Owen R. Cheatham Professor of the Sciences, Chief)

  2. Albert Einstein College of Medicine, Bronx, New York, USA

    Donna Mildvan MD (Professor of Medicine, Chief) (Professor of Medicine, Chief)

  3. Division of Infectious Diseases, Beth Israel Medical Center, New York, New York, USA

    Donna Mildvan MD (Professor of Medicine, Chief) (Professor of Medicine, Chief)

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer Science+Business Media New York

About this chapter

Cite this chapter

Krown, S.E., Paredes, J. (2001). AIDS-Associated Malignancies. In: Mandell, G.L., Mildvan, D. (eds) Atlas of AIDS. Current Medicine Group, London. https://doi.org/10.1007/978-1-4757-4549-8_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-4549-8_16

  • Publisher Name: Current Medicine Group, London

  • Print ISBN: 978-1-4757-4551-1

  • Online ISBN: 978-1-4757-4549-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation