Atlas of AIDS pp 143-153 | Cite as

Neurologic Manifestations

  • David M. Simpson
  • Susan Morgello
  • Michele Tagliati


Human Immunodeficiency Virus Human Immunodeficiency Virus Infection Progressive Multifocal Leukoencephalopathy Primary Central Nervous System Lymphoma Acquire Immunodeficiency Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Johnson RD, McArthur JC, Narayano C.: The neurobiology of human immunodeficiency virus infections. FASEB J 1988, 2:2970–2981.PubMedGoogle Scholar
  2. 2.
    McArthur JC, Cohen BA, Farzedegan H, et al.: Cerebrospinal fluid abnormalities in homosexual men with and without neuropsychiatric findings. Ann Neurol 1988, 23(suppl):534–537.CrossRefGoogle Scholar
  3. 3.
    Sidtis JJ, Gatsonis C, Price RW, et al.: Zidovudine treatment of the AIDS dementia complex: Results of a placebo-controlled trial. Ann Neurol 1993, 33:343–349.PubMedCrossRefGoogle Scholar
  4. 4.
    Dal Pan PJ, McArthur JH, Aylward E, et al.: Patterns of cerebral atrophy in HIV-1 infected individuals: Results of a quantitative MRI analysis. Neurology 1992, 42:2125–2130.PubMedCrossRefGoogle Scholar
  5. 5.
    Navia BA, Cho ES, Petite CK, Price RW: The AIDS dementia complex: II. Neuropathology. Ann Neurol 1986, 19:525–535.PubMedCrossRefGoogle Scholar
  6. 6.
    McArthur JC, McClernon DR, Cronin MF, et al.: Relationship between HIV-associated dementia and viral load in cerebrospinal fluid and brain. Ann Neurol 1997, 42:689–698.PubMedCrossRefGoogle Scholar
  7. 7.
    Belman A, Lantos G, Horoupian D, et al.: Calcification of the basal ganglia in infants and children. Neurology 1986, 36:1192–1199.PubMedCrossRefGoogle Scholar
  8. 8.
    Sharer LR, Epstein LG, Cho ES, et al.: Pathologic features of AIDS encephalopathy in children: Evidence for LAV/HTLV-II1 infection of brain. Hum Pathol 1986, 17:271–284.PubMedCrossRefGoogle Scholar
  9. 9.
    Petite CK, Navia BA, Cho ES, et al.: Vacuolar myelopathy pathologically resembling subacute combined degeneration in patients with the acquired immunodeficiency syndrome. N Engl J Med 1985, 312:874–879.CrossRefGoogle Scholar
  10. 10.
    DiRocco A, Taglioti M, Danss F, et al.: A pilot study of L-methionine for the treatment of AIDS-associated myelopathy. Neurology 1998, 51:266–268.CrossRefGoogle Scholar
  11. 11.
    Schaumberg HH, Spencer PS, Thomas PK (eds.): Anatomical classification of PNS disorder. In Disorders of Peripheral Nerves. Philadelphia: FA Davis, Co; 1983.Google Scholar
  12. 12.
    Simpson D, Citak K, Godfrey E, et al.: Myopathies associated with human immunodeficiency virus and zidovudine: Can their effects be distinguished? Neurology 1993, 43:971–976.PubMedCrossRefGoogle Scholar
  13. 13.
    Morgello S, Cho ES, Nielsen S, et al.: Cytomegalovirus encephalitis in patients with acquired immunodeficiency syndrome: An autopsy study of 30 cases and a review of the literature. Hum Pathol 1987, 18:289–297.PubMedCrossRefGoogle Scholar
  14. 14.
    Miller R, Storey J, Greco C.: Ganciclovir in the treatment of progressive AIDS-related polyradiculopathy. Neurology 1990, 40:569–574.PubMedCrossRefGoogle Scholar
  15. 15.
    Luft B, Hafner R, Korzun A, et al.: Toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome. N Engl J Med 1993, 329:995–1000.PubMedCrossRefGoogle Scholar
  16. 16.
    Navia BA, Petite CK, Gold JWM, et al.: Cerebral toxoplasmosis complicating the acquired immunodeficiency syndrome: Clinical and neuropathogical findings in 27 patients. Ann Neurol 1986, 19:224–238.PubMedCrossRefGoogle Scholar
  17. 17.
    Clofford DV, Yiannoutsos C, Glocksman M, et al.: HAART improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. Neurology 1999, 52:623–625.Google Scholar
  18. 18.
    Berger J, Kaszovitz B, Post J, Dickinson G: Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. Ann Intern Med 1987, 107:78–87.PubMedCrossRefGoogle Scholar
  19. 18.
    Hair LS, Nuovo G, Powers JM, et al.: Progressive multifocal leukoencephalopathy in patients with human immunodeficiency virus. Hum Pathol 1992, 23:663–667.PubMedCrossRefGoogle Scholar
  20. 19.
    Powderly W, Saag M, Gretcher G, et al.: A controlled trial of fluconazole or amphotericin-B to prevent relapse of cryptococcal meningitis in patients with the acquired immunodeficiency syndrome. N Engl J Med 1992, 326:793–798.PubMedCrossRefGoogle Scholar
  21. 20.
    Morgello S, Laufer H: Quaternary neurosyphilis in a Haitian man with human immunodeficiency virus infection. Hum Pathol 1989, 20:805–811.CrossRefGoogle Scholar
  22. 21.
    Berenguer J, Moreno S, Laguna F, et al.: Tuberculous meningitis in patients infected with the human immunodeficiency virus. N Engl J Med 1992, 26:668–672.CrossRefGoogle Scholar
  23. 22.
    Baumgarten J, Rachlin J, Beckstead J, et al.: Primary central nervous system lymphomas: Natural history and response to radiation therapy in 55 patients with acquired immunodeficiency syndrome. J Neurosurg 1990, 73:206–211.CrossRefGoogle Scholar
  24. 23.
    Morgello S, Petito CK, Mouradian JA: Central nervous system lymphoma in the acquired immunodeficiency syndrome. Clin Neuropathol 1990, 9(4):205–215.PubMedGoogle Scholar
  25. 24.
    MacMahon EME, Glass JD, Haywards SD, et al.: Epstein-Barr virus in AIDS-related primary central nervous system lymphoma. Lancet 1991, 338:969–973.PubMedCrossRefGoogle Scholar

Selected Bibliography

  1. Budka H, Wiley CA, Kleinves P, et al.: HIV-associated disease of the nervous system: Review of nomenclature and proposal for neuropathology-based terminology. Brain Pathol 1991, 1 (3): 143–152.PubMedCrossRefGoogle Scholar
  2. DeGirolami U, Smith TW, Henin D, Hauw JJ: Neuropathology of the acquired immunodeficiency syndrome. Arch Pathol Lab Med 1990, 114:643–655.Google Scholar
  3. Epstein LG, Gendelman HE: Human immunodeficiency virus type 1 infection of the nervous system: Pathogenetic mechanisms. Ann Neurol 1993, 33:429–436.PubMedCrossRefGoogle Scholar
  4. Simpson DM, Olney RK: Peripheral neuropathies associated with human immunodeficiency virus infection. In Dyck PJ (ed.): Peripheral Neuropathies: New Concepts and Treatments. Philadelphia: WB Saunders; 1992:685–711.Google Scholar
  5. Simpson DM, Tagliati M: Neurologic manifestations of HIV infection. Ann Intern Med 1994, 121(10):769–785.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • David M. Simpson
  • Susan Morgello
  • Michele Tagliati

There are no affiliations available

Personalised recommendations