Treatment of Pancreatic Exocrine Disorders by Pancreas and Islet Transplantation

  • Rainer W. G. Gruessner


In the 1960s and 1970s, because of the vast and complex spectrum of complications frequently associated with surgery of the native pancreas, pancreas transplants only gradually gained acceptance in the surgical community; initially, their development trailed the more rapid progress with other solid organs (kidney, liver, heart). As recently as the 1980s, the high technical complication rate of pancreas transplants seemed to confirm those early concerns. But, in the 1990s, continuous improvements in surgical techniques, the use of more efficient antimicrobial prophylaxis, and the introduction of less toxic immunosuppressive agents made life-threatening surgical complications the exception rather than the rule.


Chronic Pancreatitis Pancreatic Head Total Pancreatectomy Pancreas Transplant Insulin Independence 
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© Springer Science+Business Media New York 2004

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  • Rainer W. G. Gruessner

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