Quality of Life for Pancreas Recipients

  • Cynthia R. Gross
  • Angelika C. Gruessner
  • Charoen Treesak


Patients coping with the restrictions of the diabetic lifestyle and concerned about secondary complications are increasingly turning to pancreas transplantation (PTx). Over 13,000 pancreas transplants have been reported worldwide,1 about 10,000 in the United States alone. The vast majority of these (about 95%) are combined with renal transplants, usually as simultaneous pancreas—kidney (SPK) transplants. Patients with diabetes and uremia seek to escape the double burdens of dialysis and exogenous insulin therapy through transplantation. National statistics show that SPK affords a long-term survival advantage over a cadaver kidney transplant alone (KTA) (about 10 years) and over dialysis (about 15 years).2 Recent and younger patients are predicted to have the most benefit, as technical success and early posttransplant survival with SPK transplants improved significantly over the past decade.1,2 Studies describing the quality of life (QOL) outcomes of PTx recipients have been regularly reported since 1989. With few exceptions, all QOL reports have focused on adults with insulin-dependent diabetes mellitus (IDDM) and renal dysfunction. A number of reviews specific to PTx3–6 or transplants in general78 have synthesized the findings from many of these studies. This review will update an earlier review,4 by incorporating reports from the last 5 years. This review will address the following four questions:
  1. 1.

    What aspects of QOL change from pretransplant to posttransplant with PTx?

  2. 2.

    Which QOL benefits are transitory, sustained, or enhanced over the long term?

  3. 3.

    Are the QOL outcomes of PTx patients any different from the outcomes of kidney transplant (KTx) recipients with IDDM?

  4. 4.

    How do the outcomes of PTx recipients differ from the QOL reports of age-matched samples from the general population?



Transplant Proc Pancreas Transplant Pancreas Graft Pancreas Transplant Alone Sickness Impact Profile Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Cynthia R. Gross
  • Angelika C. Gruessner
  • Charoen Treesak

There are no affiliations available

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