Active Cochlear Feedback: Required Structure And Response Phase

  • J. J. Zwislocki
Part of the Lecture Notes in Biomathematics book series (LNBM, volume 87)


According to indirect experimental evidence, derived mainly from acoustic cochlear emissions (Kemp,1978), wave propagation in the cochlea is supported by metabolic energy. The motility of ORCs associated with an alternating electrical field (Brownell et al. 1985) is likely to be the mechanism for the energy delivery (e.g. Ashmore,1986). If the cells respond mechanically to the alternating electrical fields they themselves generate, conditions for an electromechanical feedback are provided. Several models of the feedback were proposed in the past (e.g. Kim et al., 1980; Mountainet ale 1983; Neely and Kim, 1986) but were not sufficiently explicit to establish the required structural and phase conditions. Analysis of these conditions and an experimental confirmation of its crucial results are the subject of this article.


Outer Hair Cell Basilar Membrane Spiral Ligament Tectorial Membrane Reticular Lamina 
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  1. Ashmore, J.F. (1986) The cellular physiology of isolated outer hair cells: Implications for cochlear frequency selectivity. In: Auditory Frequency Selectivity (Eds: Moore, B.C.J. and Patterson, R.D.) Plenum Press, London, pp. 103–108.Google Scholar
  2. Brownell, W.E., Bader, C.R .. Bertrand, D. and Ribaupiere, Y. (1985) Evoked mechanical responses of isolated cochlear hair cells. Science 227, 194–196.Google Scholar
  3. Brundin. L.. Flock. A., and Canlon, B. (1990) Sound induced motility of cochlear outer hair cells shows tuning. ARO Abstracts 13, 227.Google Scholar
  4. Kemp, D.T. (1978) Stimulated acoustic emissions from within the human auditory system. J. Acous!. Soc Am. 65. 1386–1391. Kemp, D.T. and Chum, R. (1980) Properties of the generator of stimulated acoustic emissions. In: Nonlinear and Active Mechanical Processes in the Cochlea (Eds: Kemp, D.T. and Anderson, S.D.) Hearing Res. 2, 213–232.Google Scholar
  5. Kim, D.,., Neely, S.T., Molnar, C.E. and Matthews, J.W. (1980) An active cochlear model with negative damping in the partition: Comparison with Rhode’s ante– and post–mortem observations. In: Psychophysical, Physiological and Behavioral Srudies in Hearing (Eds: Brink, G. v.d. and Bilsen, F.A.) Delft University Press, Delft, pp. 7 –15.Google Scholar
  6. Long, R.R. and Tubis, A. (1988) Modification of spontaneous and evoked otoacoustic emissions and associated psychoacoustic microstrucrure by aspirin consumption. J. Acoust. Soc. Am. 84, 1343–1353.Google Scholar
  7. Miller, C.E. (1985) Strucrural implications of basilar membrane compliance measurements. J. Acoust. Soc. Am. 77, 1465–1474.Google Scholar
  8. Mountain, D.C., Hubbard,A.E. and McMullen, T.A. (1983) Electromechanical processes in the cochlea. In: Mechanics of Hearing (Eds: de Boer, E. and Viergever, M.A.) Delft University Press, Delft, pp. 119–126.Google Scholar
  9. Neely, S.T. and Kim, D.,. (1986) A model for active elements in cochlear biomechanics. J. Acoust. Soc. Am. 79, 1472–1480.Google Scholar
  10. Shehata, W.E., Brownell, W.E., Cousillas, H. and Imredy, J.P. (1990) Salicylate alters membrane conductance of outer hair cells and diminishes rapid electromotile responses. ARO Abstracts 13, 252–253.Google Scholar
  11. Zwislocki, J.J. (1980) Five decades of research on cochlear mechanics. J. Acoust. Soc. Am. 67, 1679–1685.Google Scholar
  12. Zwislocki, J.J. (1988) Phase reversal of OHC response at high sound intensities. In: Cochlear Mechanisms: Structure, Function and Models (Eds: Wilson, J.P. and Kemp, D.T.) Plenum Press, London, pp. 163–168.Google Scholar
  13. Zwislocki, J.J. and Cefaratti, L.K. (1989) Tectorial membrane II: Stiffness measurements in vivo. Hearing Res. 42, 211–228.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • J. J. Zwislocki
    • 1
  1. 1.Institute for Sensory ResearchSyracuse UniversitySyracuseUSA

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