Present Status of Anticoagulant Prophylaxis

  • J. Donald Easton


Although anticoagulation is widely used for stroke prevention, it has not been well studied and is substantially unproven in the management of cerebral vascular diseases. Even after nearly 40 years of use, major controversy questions its value in preventing infarction in patients with transient ischemic attack (TIA), in arresting progressing stroke, and in preventing cerebral reinfarction. Although most clinicians believe anticoagulants are effective in some situations, they question how well they work, and whether the bleeding risks outweigh the benefit. Anticoagulation using heparin and warfarin and the justification for its current role in the treatment of cerebral vascular disease will be reviewed in this chapter.


Atrial Fibrillation Transient Ischernic Attack Stroke Prevention Rheumatic Heart Disease Cerebral Venous Thrombosis 
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© Springer Science+Business Media New York 1991

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  • J. Donald Easton

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