• S. T. Treves
  • L. P. Connolly
  • J. A. Kirkpatrick
  • A. B. Packard
  • P. Roach
  • D. Jaramillo


Skeletal scintigraphy is a highly sensitive technique for the diagnosis of bone disorders in children. Since the introduction of technetium-99m (99mTc)-labeled phosphates in 1971157, skeletal scintigraphy has become one of the most common examinations in pediatric nuclear medicine. The high sensitivity of phosphate scintigraphy is accompanied in some instances by a relatively low specificity. Hence, there has been an ongoing interest in the use of other radiopharmaceuticals with different mechanisms of uptake from those of the radiophosphates that may add specificity to the diagnosis and evaluation of certain skeletal diseases. Examples of such radiopharmaceuticals include gallium-67 (67Ga) citrate, thallium-201 (201Tl) chloride, 99mTc -methoxy-isobutyl isonitrile (MIBI), iodines-123 and -131 (123I, 131I)-metaiodobenzylguanidine, 99mTc -white blood cells (WBCs), indium-111 (111MIn)-WBCs, 99mTc -sulfur colloid, and 111In chloride.


Single Photon Emission Compute Tomography Femoral Head Tracer Uptake Septic Arthritis Fibrous Dysplasia 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • S. T. Treves
  • L. P. Connolly
  • J. A. Kirkpatrick
  • A. B. Packard
  • P. Roach
  • D. Jaramillo

There are no affiliations available

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