Molar Pregnancies

  • Kurt Benirschke
  • Peter Kaufmann


The term “gestational trophoblastic neoplasia” has become popular in recent years, although it comprises entities that are clearly not neoplastic, such as the triploid or “partial mole.” Driscoll (1981), in an excellent review of the morphology of these diseases, strongly favored abandonment of the time-honored term hydatidiform mole. Fox (1989) has added fuel to the fire by suggesting the following: “Is it, in fact, justifiable to continue distinguishing complete from partial moles in routine histopatho-logical practice?” He based this opinion primarily on the exceptional finding of a single choriocarcinoma having followed a partial mole (Looi & Sivanesratnam, 1981). This view is not mine. After all, choriocarcinoma is also an occasional sequela of an apparently “normal” gestation, as Fox readily conceded and may have been a chorio-carcinomatous cell line ab initio.


Hydatidiform Mole Gestational Trophoblastic Disease Molar Pregnancy Trophoblastic Tumor Gestational Trophoblastic Neoplasia 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Kurt Benirschke
    • 1
    • 2
  • Peter Kaufmann
    • 3
  1. 1.Pathology and Reproductive MedicineUniversity of CaliforniaSan DiegoUSA
  2. 2.University Medical CenterSan DiegoUSA
  3. 3.Institut für Anatomie der Medizinischen Fakultät, Rheinisch-Westfälische TechnischeHochschule AachenAachenGermany

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