Abstract
The use of contact lenses in treating conditions such as epithelial defects, corneal edema and dry eye syndromes has been extensively investigated. Contact lenses, by shielding the epithelium from the abrasive action of the lids, may avoid mechanical disruption of the ocular surface and aid its healing. Hydrophilic materials, acting as a fluid reservoir, are useful in dry eye syndromes when used in conjunction with frequent artificial tears instillation; sometimes they are also useful in mild degrees of corneal edema when applied in conjunction with hypertonic solutions.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Asseff C.F., Weisman R.L., Podos S.M., Becker B. (1973). Ocular penetration of pilocarpine in primates. Am. J. Ophthalmol 75: 212–225.
Bietti G.B., Romani E., Pecori-Giraldi J. (1974). Studies on the possibility of using soft contact lenses for the administration of certain therapeutic drugs. International Medical Symposium on Soft Contact Lenses, Geneva, Nov. 1–3.
Bietti G.B., Virno M., Pecori-Giraldi J., Pellegrino N., Motolese E. (1976). Possibility of isoproterenol therapy with soft contact lenses: ocular hypotension without systemic effects. Ann: Ophthalmol 8: 819–829.
Calabria G.A., Ciurlo G. (1973). Somministrazione di farmaci mediante inserti idrofili congiuntivali. Atti 55 Congr. Soc. Oftalmol. Italiana 29: 320–326.
Cerulli L., Bagella G., Melis M., Fasulo R., Scuderi G.L. (1981b). Influenza delle variazioni della temperatura e del pH sulla farmacodinamica in vitro di antibiotici veicolati da lenti a contatto morbide. Clin. Oc. 2: 38–40.
Cerulli L., Bagella G., Fasulo R., Scuderi G.L. (1981a). Farmacodinamica di antibiotici veicolati da lenti a contatto a diverso potere idrofilo. Clin. Oc. 2: 257–260.
Cerulli L., Bagella G., Fasulo R., Martelli M. (1983). Studio sulla farmacodinamica in vitro della citosin-arabinoside veicolata da lenti a contatto morbide per il trattamento delle cheratiti erpetiche. Clin. Oc. 4: 231–234.
Ellis P.P., Matsumura M., Rendi M.A. (1985). Pilocarpine concentration in aqueous humor following single drop application. I - Effect of soft contact lenses. Curr. Eye Res. 4: 1041–1047.
François J., Cambie E. (1971). New prospectives in the treatment of corneal ulcers. T. Geneesk. 27. 1070–1074.
Gasset A., Kaufman H., (1970). Therapeutic use of hydrophilic contact lenses. Am. J. Ophthalmol. 69: 252–259.
Hales R.H. (1982). Contact lenses. A clinical approach to fitting. Baltimore, Williams and Wilkins pp. 252–259.
Harris J. (1968). In: Symposium on ocular therapy. ed. I.H. Leopold, Mosby, St. Louis, Vol. 3, p. 99.
Hillman J.S, (1974). Management of acute glaucoma with pilocarpine -soaked hydrophilic lens. Br. J. Ophthalmol. 58: 674–679.
Hillman J.S. (1975). Pilocarpine delivery by hydrophilic lens in management of acute glaucoma. Trans Ophthalmol. Soc. U.K. 95: 7984.
Hovding G. (1983). The fluid content of hydrophilic contact lenses on the eye. Acta Ophthalmol. (Copenh). 61: 881–891.
Kaufman H.E., Uotila M.H., Gasset A.R., Wood T.O., Ellison E.D. (1971). The medical use of soft contact lenses. Trans. Am. Acad. Ophthalmol. Otolaryngol. 75: 361–373.
Lerman S., Reininger B. (1971). Simulated sustained release pilocarpine therapy and aqueous humor dynamics. Can. J. Opthalmol. 6: 14–23.
Matoba A.Y., McCulley J.P. (1985). The effect of therapeutic soft contact lenses on antibiotic delivery to the cornea. Ophthalmology 92: 97–99.
Mc Carey B.E., Wilson L.A. (1982). pH, osmolarity and temperature effects on the water content of hydrogel contact lens. Contact and Intraocular Lens Med. J. 8: 158–167.
Mc Carey B.E., Schmidt F.H., Wilkinson K.D., Baum J.P. (1984). Gentamicin diffusion across hydrogel bandage lenses and its kinetic distribution on th eye. Curr. Eye Res. 3: 977–989.
North D.P. (1971). Can. Med. Ass. J. 105: 561.
Podos S.M., Becker B., Asseff C., Hartstein J. (1972). Pilocarpine therapy with soft contact lenses. Am. J. Ophthalmol. 73: 336–341.
Sedlacek J. (1965). Possibilities of application of ophthalmic drugs with aid of gel-contact-lenses. Cs. Optalmol. 21: 509–912.
Smith S.G., Lindstrom R.L., Doughman D.G. (1982). Keratoplasty. Letter to the Editor. Ophthalmic Surg. 13: 61.
Sorensen T.B., Jensen F.T. (1980). Lacrimal pathology evaluated by dynamic lacrimal scintigraphy. Acta Ophthalmol. ( Copenh ) 58: 597–607.
Sorensen T.B., Jensen F.T., Margversen J. (1980). A human and in vitro study on the exchange of water and solutes from soft contact lenses. Acta Ophthalmol. ( Copenh ) 58: 576–587.
Sorensen T.B. (1984). Studies on tear physiology, pathophysiology and contact lenses by means of dynamic gamma camera and technetium. Acta Ophthalmol Supp: 167: 1–53.
Waltman S., Kaufman H. (1970). Use of hydrophilic contact lenses to increase ocular penetration of topical drugs. Invest. Ophthalmol. 9. 250–255.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Springer Science+Business Media New York
About this paper
Cite this paper
Calabria, G., Rathschuler, F. (1987). Contact Lenses as Therapeutic Systems. In: Saettone, M.F., Bucci, M., Speiser, P. (eds) Ophthalmic Drug Delivery. FIDIA Research Series, vol 11. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4175-9_8
Download citation
DOI: https://doi.org/10.1007/978-1-4757-4175-9_8
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-4177-3
Online ISBN: 978-1-4757-4175-9
eBook Packages: Springer Book Archive