Abstract
The emerging discipline of gerontology is receiving increasing attention. Aging can be thought of as a natural progressive deterioration that may be genetically programmed. The question is, when does “aging” begin? There are genetic syndromes in humans with many features of accelerated aging, such as Downs syndrome and progeria (1). In this context, it is thought that motoneuron aging is programmed genetically, but that secondary factors may influence the time course (e.g., exhaustion of motoneurons following increased metabolic demands).
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Giaquinto S: Aging and the Nervous System. New York, John Wiley & Sons, 1988.
McComas AJ, Lipton ARM, Sica REP: Motoneuron disease and aging. Lancet 1973;2:1477–1480.
Groher ME, Bukatman R: The prevalence of swallowing disorders in two teaching hospitals. Dysphagia 1986;1:3–6.
Malmgren LT: Aging related changes in peripheral nerves in the head and neck, in Goldstein JC, Kashima HK, Koopmann CF (eds): Geriatric Otorhinolaryngology. Toronto, Brian C. Decker Inc, 1989.
Pontoppidan H, Beecher HK: Progressive loss of protective reflexes in the airway with the advance of age. JAMA 1960;174:2209–2213.
Kashima HK: Presbyphagia, introduction, in Goldstein JC, Kashima HK, Koopmann CF (eds): Geriatric Otorhinolaryngology. Toronto, Brian C. Decker Inc, 1989.
Rosenheimer JL, Smith DO: Differential changes in the end-plate architecture of functionally diverse muscles during aging. J Neurophysiol 1985;53:1567–1581.
Baum BJ, Bodner L: Aging and oral motor function: Evidence for altered performance among older persons. J Dental Res l983;62(1):2–6.
Osterberg T, Carlsson G: Symptoms and signs of mandibular dysfunction in 70-year old men and women in Gothenburg, Sweden. Community Dent Oral Epidemiol 1979;7:315–321.
Rolls BJ: Regulation of food and fluid intake in the elderly: Nutrition and the chemical senses, in Aging: Recent Advances and Current Research Needs, publ no. 561. New York, The New York Academy of Sciences, 1989, pp 217–225.
Kaplan H: The oral cavity in geriatrics. Geriatrics 1971;26:96–102.
Tracy JF, Logemann JA, Kahrilas PJ, Kobara M, Krugler C: Preliminary observations on the effects of age on oropharyngeal deglutition. Dysphagia 1989;4:90–94.
Feldman RS, Kapur KK, Alman JE, et al: Aging and mastication changes in performance and in the swallowing threshold with natural dentition. J Am Geriatr Soc 1980;28(3):96–102.
Shaker R, Dodds WJ, Hogan WJ, Stemper AK: Effect of aging on swallow induced lingual palatal closure pressure. Gastroenterology 1989;96:A464.
Buchholz DW, Donner MW, Bosma JF: Adaption, compensation and decompensation of the pharyngeal swallow. Gastrointest Radiol 1985;10:235–239.
Ferreri G: Senescence of the larynx. Ital Gen Rev Otorhinolaryngol 1959;1:640–709.
Kahane JC: Postnatal development and aging of the human larynx. Semin Speech Lang 1983;4:189–203.
Borgstrom PS, Ekberg O: Pharyngeal dysfunction in the elderly. J Med Imaging 1988;2:74–81.
Sonies BC, Stone, M, Shawker T: Speech and swallowing in the elderly. Gerodontology 1984;3:115–123.
Borgstrom PS, Ekberg O: Speed of peristalsis in pharyngeal constrictor musculature: Correlations to age. Dysphagia 1988;2:140–144.
Hellemans J, Vantrappen G: Presbyesophagus, in Diseases of the Esophagus. Berlin, SpringerVerlag, 1974, pp 372–378.
Zboralske FF, Amberg JR, Soergel KH: Presbyesophagus: Cine-radiographic manifestations. Radiology 1964;82:463–467.
Mandelstam P, Lieber A: Cineradiographic evaluation of the esophagus in normal adults. Gastroenterology 1970;58:32–39.
Geokas MC, Conteas CN, Majundar APN: The aging gastrointestinal tract, liver, and pancreas. Clin Geriatr Med 1985;1:177–205.
Eckardt VF, LeCompte PM: Histology of esophageal smooth muscle and Auerbach’s plexus in elderly persons. Gastroenterology 1977;72:1055.
Hollis JB, Castell DO: Esophageal function in elderly men: A new look at presbyesophagus. Ann Intern Med 1974;80:371.
Khan TA, Shragge RW, Crispin JS, Lind JF: Esophageal motility in the elderly. Am J Dig Dis 1977;22:1049–1054.
Soergel KH, Zboralske FF, Auberg JR: Presbyesophagus: Esophageal motility in nonagenarians. J Clin Invest 1964;43:1472–1479.
Buchholz D: Neurologic causes of dysphagia. Dysphagia 1987;1:152–156.
Kirshner S: Causes of neurogenic dysphagia. Dysphagia 1989;3:184–188.
Silbiger ML, Pikheney R, Donner MW: Neuromuscular disorders affecting the pharynx: Cineradiographic analysis. Invest Radiol 1967;2:442–448.
Veis SL, Logemann JA: Swallowing disorders in persons with cerebrovascular accident. Arch Phys Med Rehabil 1985;66:372–375.
Gordon C, Hewer RL, Wade DT: Dysphagia in acute stroke. Br Med J 1987;295:411–414.
Robbins JA, Levine RL: Swallowing after unilateral stroke of the cerebral cortex: Preliminary experience. Dysphagia 1988;3:11–17.
Daly DD, Code CF, Anderson HA: Disturbances of swallowing and esophageal motility in patients with multiple sclerosis. Neurology 1962;59:250–256.
Lieberman AN, Horowitz L, Redmond P, Pachter L, Lieberman I, Leibowitz M: Dysphagia in Parkinson’s disease. Am J Gastroenterol 1980;74:157–160.
Leopold NA, Kagel MC: Dysphagia in Huntington’s disease. Neurology 1985;42:57–60.
Dalakas MC, Elder G, Hallett M, Ravits J, Baker M, Papadopoulos N, Albrecht P, Sever J: A longterm follow-up study of patients with post-poliomyelitis neuromuscular symptoms. N Engl J Med 1986;314:959–963.
Cashman NR, Maselli R, Wollmann RL, Roos R, Simon R, Antel JP: Late denervation in patients with antecedent paralytic poliomyelitis. N Engl J Med 1987;317:7–12.
McQuillen MP, Cantor HE, O’Rourke JR Jr: Myasthenic syndrome associated with antibiotics. Arch Neurol 1968;18:402–415.
Pittinger CB, Eryase Y, Adamson R: Antibiotic induced paralysis. Anesth Analg 1970;49:487.
Swift TR: Disorders of neuromuscular transmission other than myasthenia gravis. Muscle Nerve 1981;4:334.
Adams RD, Victor M: Principles of Neurology, ed 4. New York, McGraw-Hill, 1989.
Murray JP: Deglutition in myasthenia gravis. Br J Radiol 1962;35:43–52.
Eaton LM, Lambert EH: Electromyography and electric stimulation of nerves and diseases of motor unit: Observations on myasthenia syndrome associated with malignant tumors. JAMA 1957;163:1117.
Jacob H, Berkowitz D, McDonald E, Bernstein L, Beneventano T: The esophageal motility disorder of polymyositis: A prospective study. Arch Intern Med 1983;143:2262–2264.
Merieux P, Verity M, Clements P, Paulus H: Esophageal abnormalities and dysphagia in polymyositis and dermamyositis: Clinical, radiographic, and pathologic features. Arthritis Rheum 1983;26:961–968.
Hertzman PA, Blevins WL, Mayer J, Greenfield B, Ting M, Gleich GJ: Association of the eosinophilia-myalgia syndrome with the ingestion of tryptohan. N Engl J Med 1990;322:869–873.
Siegel Cl, Hendrix TR, Harvey JC: The swallowing disorder in myotonia dystrophica. Gastroenterology 1966;50:541–550.
Duranceau A, Jamieson G, Clermont RJ: Oropharyngeal dysphagia in patients with oculopharyngeal muscular dystrophy. Can J Surg 1978;21:326–329.
Suggested Reading
Bartlett JG, Gorbach SL: The triple threat of aspiration pneumonia. Chest 1975;68:560–566.
Braman SS, Davis SM: Wheezing in the elderly. Respiratory diseases. Geriatr Clin North Am 1986;2:269–283.
Branchine JR, Brys DA, Schwarz RD, Enianya DT, Duran DO, Greenwald JE, Andresen BD: Clinical correlates of changes in receptors during aging, in Adelman RC, Roberts J, Baker GT III, Baskin SI, Cristofalo VJ (eds): Neural Regulatory Mechanisms during Aging. Modern Aging Series, Vol. I. New York, Alan R. Liss, Inc, 1980, pp 129–141.
Elliott JL: Swallowing disorders in the elderly: A guide to diagnosis and treatment. Geriatrics 1988;43:95–100.
Margulies SI, Brunt PW, Donner MW, Silbiger ML: Familial dysautonomia: A cineradiographic study of the swallowing mechanism. Radiology 1968;90:107–112.
Patel GK, Diner WC, Texter EC Jr: Swallowing and pharyngoesophageal function in the aging patient, in Texter EC Jr (ed): The Aging Gut. Paris, Masson Publishers USA, Inc, 1983.
Sheth N, Diner WC: Swallowing problems in the elderly. Dysphagia 1988;2:209–215.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer Science+Business Media New York
About this chapter
Cite this chapter
Donner, M.W., Jones, B. (1991). Aging and Neurological Disease. In: Jones, B., Donner, M.W. (eds) Normal and Abnormal Swallowing. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4150-6_12
Download citation
DOI: https://doi.org/10.1007/978-1-4757-4150-6_12
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-4152-0
Online ISBN: 978-1-4757-4150-6
eBook Packages: Springer Book Archive