Binding Studies of Integrins with Their Respective Ligands

  • Kirsten Tangemann
  • Jürgen Engel


In vitro investigations of interactions between isolated protein components offer the attractive feature that the system is characterized by a defined set of parameters. Binding data are therefore much easier to understand than data derived from assay systems with cells. In in vivo experiments in which the complexity of the system may be very large and difficult to oversee, often it is not possible to control parameters like pH, ion concentration or temperature.


Surface Plasmon Resonance Sensor Chip Scatchard Plot Total Internal Reflection Fluorescence Microscopy Respective Ligand 
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© Springer Science+Business Media Dordrecht 1997

Authors and Affiliations

  • Kirsten Tangemann
  • Jürgen Engel

There are no affiliations available

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