• John Saultz


Everyone experiences fatigue periodically as a result of hard physical labor or loss of sleep. Fatigue, loss of energy, and lassitude are common symptoms experienced by patients with any one of a large number of diseases. A patient who complains of chronic fatigue presents a difficult problem for the family physician because there are many possible explanations for the fatigue. This difficulty is compounded by the subjective nature of the complaint and the potential seriousness of some of the diseases in the differential diagnosis.


Chronic Fatigue Syndrome Family Physician Chief Complaint Rheumatic Heart Disease Mitral Valve Prolapse 
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  1. 1.
    National Ambulatory Medical Care Survey: 1975 Summary. U.S. Department of Health and Human Services Publ. 78–1784, 1978.Google Scholar
  2. 2.
    Kroenke K, Wood DR, Mangelsdorf D, et al. Chronic fatigue in primary care. JAMA 1988;260:929–34.PubMedCrossRefGoogle Scholar
  3. 3.
    Valdini AF, Steinhardt S, Valicenti J, Jaffe A. One year follow-up of fatigued patients. J Fam Pract 1988;26:33–8.PubMedGoogle Scholar
  4. 4.
    Shahar E, Lederer J. Asthenic symptoms in a rural family practice. J Fam Pract 1990;31:257–62.PubMedGoogle Scholar
  5. 5.
    Straus SE. The history of chronic fatigue syndrome. Rev Infect Dis 1991;13 Suppl 1:S2–S7.CrossRefGoogle Scholar
  6. 6.
    Holmes GP, Kaplan JE, Gantz NM, et al. Chronic fatigue syndrome: a working case definition. Ann Intern Med 1988;108:387–9.PubMedCrossRefGoogle Scholar
  7. 7.
    Manu P, Lane TJ, Matthews DA. The frequency of chronic fatigue syndrome in patients with persistent fatigue. Ann Intern Med 1988;109:554–6.PubMedCrossRefGoogle Scholar
  8. 8.
    Kirk J, Douglas R, Nelson E, et al. Chief complaint of fatigue, a prospective study. J Fam Pract 1990;30:33–41.PubMedGoogle Scholar
  9. 9.
    Jerrett WA. Lethargy in general practice. Practitioner 1981;225: 731–7.PubMedGoogle Scholar
  10. 10.
    Morrison JD. Fatigue as a presenting complaint in family practice. J Fam Pract 1980;10:795–801.PubMedGoogle Scholar
  11. 11.
    Sugarman JR, Berg AD. Evaluation of fatigue in a family practice. J Fam Pract 1984;19:643–7.PubMedGoogle Scholar
  12. 12.
    Jones JF. Serologic and immunologic responses in chronic fatigue syndrome with emphasis on the Epstein-Barr virus. Rev Infect Dis 1991;13 Suppl 1:506–31.Google Scholar
  13. 13.
    Buchwald D, Komaroff AL. Review of laboratory findings for patients with chronic fatigue syndrome. Rev Infect Dis 1991; 13 Suppl 1:S12–S18.CrossRefGoogle Scholar
  14. 14.
    Sumaya CV. Serologic and virologie epidemiology of Epstein-Barr virus: relevance to chronic fatigue syndrome. Rev Infect Dis 1991;13 Suppl 1:519–25.Google Scholar
  15. 15.
    Buttler S, Chalder T, Ron M, Wessley S. Cognitive behavior therapy in chronic fatigue syndrome. J Neurol Neurosurg Psychiatry 1991;54:153–8.CrossRefGoogle Scholar

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© Springer Science+Business Media New York 1994

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  • John Saultz

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