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Selected Disorders of the Blood and Hematopoietic System

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Abstract

Hemophilia A is an autosomal recessive X-linked deficiency of factor VIII. Because of the mode of transmission and gene expression, males have hemophilia A, and females are usually asymptomatic carriers of the hemophilia A gene. All daughters of a hemophiliac father are carriers of the hemophilia A gene; all his sons are normal. The children of a female hemophilia A carrier have a 50% chance of being affected by the gene. Hemophilia A affects approximately 1 in 10,000 to 20,000 males in the United States.1

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Authors
  1. Paul M. Paulman
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  2. Nancy Wolf-Gillespie
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  3. Layne A. Prest
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Editor information

Editors and Affiliations

  1. Department of Family Medicine, Oregon Health Sciences University, School of Medicine, Portland, 97201, OR, USA

    Robert B. Taylor M.D. (Professor and Chairman) (Professor and Chairman)

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© 1994 Springer Science+Business Media New York

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Paulman, P.M., Wolf-Gillespie, N., Prest, L.A. (1994). Selected Disorders of the Blood and Hematopoietic System. In: Taylor, R.B. (eds) Family Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4005-9_127

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  • DOI: https://doi.org/10.1007/978-1-4757-4005-9_127

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-4007-3

  • Online ISBN: 978-1-4757-4005-9

  • eBook Packages: Springer Book Archive

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