Most endometrial polyps appear to originate from localized hyperplasia of the basalis, although their pathogenesis is not well understood. Polyps occur over a wide age range, but are most common in women in the fourth and fifth decades, becoming less frequent after age 60.1–3 Usually they present with abnormal uterine bleeding.4 They have been implicated as a cause of abnormal bleeding in between 2 % and 23% of patients coming to biopsy.2,5–7 They also have been implicated as a possible cause of infertility, either by physically interfering with blastocyst implantation or by altering the development of secretory phase endometrium, making it less receptive to the implanting embryo.8–11 A few endometrial polyps have been found in patients receiving tamoxifen therapy for breast carcinoma.12,13 Large polyps that extend into the endo-cervix and dilate the internal os can cause endometritis.


Hyperplastic Polyp Endometrial Polyp Large Polyp Normal Endometrium Lower Uterine Segment 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Michael T. Mazur
    • 1
  • Robert J. Kurman
    • 2
    • 3
  1. 1.Crouse Irving Memorial Hospital, Health Science CenterState University of New YorkSyracuseUSA
  2. 2.Departments of Gynecology and Obstetrics and PathologyThe Johns Hopkins HospitalBaltimoreUSA
  3. 3.The Johns Hopkins University School of MedicineBaltimoreUSA

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