Abstract
There are several methods of sampling the endometrium. The “gold standard” is dilatation and curettage (D&C), which requires dilatation of the cervix to allow insertion of a curette into the endometrial cavity.1–5 This technique allows for the most thorough sampling of the endometrium but requires anesthesia for cervical dilatation. The curette is drawn across the anterior and posterior endometrial surfaces, scraping the tissue free. D&C also readily allows for a fractional curettage, with sampling of both the endometrial and the endocervical mucosa. Fractional sampling is especially useful for evaluating possible endocervical pathology, such as extension of endometrial adenocarcinoma to the endocervix.6
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Mazur, M.T., Kurman, R.J. (1995). Methods of Endometrial Evaluation. In: Diagnosis of Endometrial Biopsies and Curettings. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3943-5_12
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