Pneumoconioses, Mineral and Vegetable

  • Victor L. Roggli
  • John D. Shelburne


The term pneumoconiosis, originally coined by Zenker,1 literally means dust in the lung. Because various types of dust can be found in the lungs of virtually all adults, this term has come to mean the accumulation of abnormal amounts of dust in the lungs and the pathologic response to this dust. A great variety of dust particles have been identified which, when inhaled in sufficient amounts, are capable of producing disease in man. The sources of these particles are diverse, ranging from occupational to environmental exposures. Factors important in determining the pathologic response to a given dust exposure include the number, size, and physiochemical properties of the inhaled particles; the route and efficiency of clearance of the particles from the respiratory tract; the nature and intensity of the host’s inflammatory response to the particles deposited in the lung; the duration of the exposure and interval since initial exposure; and interactions between the inhaled particles from multiple sources and other environmental pollutants, such as cigarette smoke.


Tungsten Carbide Coal Dust Asbestos Fiber Open Lung Biopsy Coal Worker Pneumoconiosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Victor L. Roggli
  • John D. Shelburne

There are no affiliations available

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