Emphysema and Chronic Airways Disease

  • Philip C. Pratt


Pulmonary emphysema is among the most prevalent of all diseases. On the basis of examination of properly inflation-fixed lungs from consecutive autopsy series, it is present in at least one-third of the adult male population and in half or more of those men who smoke.1–5 This high prevalence is partly the result of the gradual evolution and progression of the lesions, which on average probably take some 30 or more years from the asymptomatic onset to the final lethal episode of respiratory failure. The prolonged course also gives many individuals the opportunity to die of other diseases so that the death rate from emphysema is far lower than the prevalence rate. Therefore, the major societal impact of the disease results not so much from total prevalence or deaths, as from the many years of disability and loss of productivity experienced by the many cases who become symptomatic in their late forties and survive with impairment throughout their fifties and sixties. The disease is less common in women, but the incidence in women has increased in recent years.5


Lower Lobe Airway Disease Small Airway Pulmonary Emphysema Alveolar Septum 
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© Springer Science+Business Media New York 1994

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  • Philip C. Pratt

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