Iatrogenic Injury: Radiation and Drug Effects

  • Rodney A. Schmidt


Virtually all therapies of modern medicine carry the potential for harm. Fortunately, the potential is usually low and the consequences are mild. Nevertheless, iatrogenic disease is common and can result in the death of patients. For example, it is estimated that the incidence of adverse drug reactions most likely lies between 10% and 20% but may range as high as 28%.1 Drug reactions cause between 2.9% and 6.2% of all hospital admissions and as many as 0.31% of all hospital deaths.1,2 A substantial fraction of drug reactions involve the respiratory system. Radiation therapy is also associated with adverse effects. Estimates of radiation pneumonitis range from 5% to 20% for patients given tumoricidal doses of thoracic radiation.3–5


Pulmonary Edema Radiation Injury Radiation Pneumonitis Obliterative Bronchiolitis Iatrogenic Injury 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Rodney A. Schmidt

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