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Fungal Infections

  • Francis W. Chandler
  • John C. Watts

Abstract

Fungi are eukaryotic, unicellular, or filamentous organisms that lack chlorophyll, have chitinous cell walls, and reproduce asexually, sexually, or both ways. All available evidence indicates that humans and animals contract most fungal infections by exposure to infectious particles originating from saprophytic moulds and yeasts growing in nature. Of more than 100,000 fungal species in our environment, only about 150 are known to be pathogenic. Their ability to invade body tissues and to produce disease depends on the virulence of the infectious particle, the infecting dose, the route of infection, the resistance or immune status of the host, the organs affected, and the coexistence of infections and other underlying medical conditions. A few fungi, such as the Candida spp., are endogenous, occurring as commensals on the skin and mucous membranes and in the gastrointestinal tract.1,2 These fungi, which are part of the normal body flora, are opportunists that only rarely infect the noncompromised, healthy individual. The Prototheca spp. are not fungi, but are considered by most taxonomists to be achloric mutants of green algae of the genus Chlorella.3 Nevertheless, diseases caused by the protothecae have traditionally fallen within the province of medical mycology and are therefore included in this chapter. For detailed information on the taxonomy of the fungi, several texts are recommended.2–5

Keywords

Invasive Aspergillosis Acquire Immune Deficiency Syndrome Invasive Pulmonary Aspergillosis Yeast Form Fungus Ball 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Francis W. Chandler
  • John C. Watts

There are no affiliations available

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