Cell Harvest and Purification Technology — State of the Art and Future Development

Conference paper
Part of the Developments in Hematology and Immunology book series (DIHI, volume 38)


Different WBC populations in human blood can be collected for cancer therapy. Hematopoietic stem/progenitor cells (HSPC), originally harvested from bone marrow, are now increasingly collected from blood for autologous and allogeneic transplantations. Umbilical cord blood, discarded until recently, has become a source of HSPC [1–4]. Recently, HSPC have been shown to have the potential to develop into cells of other organ systems [5–21]. In the laboratory, it is possible to grow cells of neural, hepatic cells, and cardiac origins from the bone marrow [20,21]. Clinical protocols are being developed to test the hypothesis of the plasticity of the HSPC.


Peripheral Blood Stem Cell Autologous Bone Marrow Peripheral Blood Progenitor Cell Cell Separation System Counterflow Centrifugal Elutriation 
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Copyright information

© Springer Science+Business Media Dordrecht 2003

Authors and Affiliations

  • P. Law
    • 1
  1. 1.Dendreon Corporation, Cell Process DevelopmentSeattleUSA

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