Future Directions: Challenges and Research Opportunities
Percutaneous vertebroplasty (PV) has created a tremendous amount of interest among patients, their families, and physicians as a means of addressing problems caused by osteoporosis or neoplasm-induced vertebral compression fractures (VCFs). However, interest in the procedure is not limited to these treatment groups. The introduction of PV in 1984, and its growing acceptance as the standard of care for the treatment of painful VCFs, have encouraged scientific investigations into the palliative mechanisms of the procedure.1–9 Manufacturers have also been eager to develop new devices to meet the demands of the procedure. In the next decade, we can expect to see a growing body of research that will expand the current knowledge about minimally invasive procedures, including (but not limited to) mechanical augmentation of the spine.10–13 We anticipate that commercial efforts will follow rapidly, with the development of new devices and materials that enhance and improve our capabilities for these interventions. This chapter presents an overview of what we believe needs to be addressed and where we are likely to see advancements.
KeywordsVertebral Body Pedicle Screw Bone Cement Percutaneous Vertebroplasty Cement Injection
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- 21.Belkoff SM, Deramond H. The effect of monomer on MCF-7 breast cancer cell viability. Poster presented at the 11th Interdisciplinary Research Conference on Biomaterials (Groupe de Recherches Interdisciplinaire sur les Biomateriaux Ostéo-articulaires Injectables, GRIBOI), March 8–9, 2001.Google Scholar
- 24.Dallap BL, Gadaleta S, Erbe E, et al. Histological, radiological, and mechanical comparison of polymethyl methacrylate (PMMA) and a bioactive bone cement in an ovine model [abstract]. Trans Orthop Res Soc 1999; 24:503.Google Scholar
- 26.Lazarus JA. A computer integrated surgical system for fluoroscopy-guided percutaneous vertebroplasty [thesis]. Johns Hopkins University, Baltimore, MD, 2000.Google Scholar
- 29.Roubertou H. Étude biomecanique in vitro d’extrémités supérieures du fémur sans et avec injection intra-osseuse de ciment acrylique. Thesis. Université de Picardie, September 12, 1997.Google Scholar
- 34.Kostuik JP, Heggeness MH. Surgery of the osteoporotic spine. In: Frymoyer JW, ed. The Adult Spine: Principles and Practice. 2nd ed. Philadelphia: Lippincott-Raven; 1997:1639–1664.Google Scholar