A pioneering paper on neurosurgical use of balloons in 1980 by Mullan et al.1 contains one of the very first descriptions of successful carotid balloon angioplasty. The same paper also describes transvenous embolization of a carotid cavernous fistula, and balloon-occlusion of an exsanguinating carotid artery. It also reports in detail a procedure for coil obliteration of an inoperable carotid aneurysm using phosphate bronze coils. The bronze coils were inserted through the aneurysm wall after direct exposure of the aneurysm at craniotomy. Intravascular balloons were used to prevent prolapse of the coils into the carotid artery and were removed at the end of the procedure. The patient had a successful recovery. This single brief paper therefore pointed the direction for a number of innovations that would be developed over the following decades. The strategy of using balloons to keep coils within an aneurysm would later be developed into the balloon reconstructive technique for endovascular aneurysm coil therapy.


Internal Carotid Artery Vertebral Artery Intracranial Aneurysm Coil Embolization Posterior Inferior Cerebellar Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Mullan S, Duda EE, Patronas NJ (1980) Some examples of balloon technology in neurosurgery. J Neurosurg 52: 321–329.PubMedCrossRefGoogle Scholar
  2. 2.
    Guglielmi G, Vinuela F, Sepetka I, Macellari V (1991) Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique, and experimental results. J Neurosurg 75: 1–7.PubMedCrossRefGoogle Scholar
  3. 3.
    Guglielmi G, Vinuela F, Dion J, Duckwiler G (1991) Electrothrombosis of saccular aneurysms via endovascular approach. Part 2: Preliminary clinical experience. J Neurosurg 75: 8–14.PubMedCrossRefGoogle Scholar
  4. 4.
    KingJT JR, Berlin JA, Flamm ES (1994) Morbidity and mortality from elective surgery for asymptomatic, unruptured, intracranial aneurysms: a meta-analysis. J Neurosurg 81: 837–842.PubMedCrossRefGoogle Scholar
  5. 5.
    Solomon RA, Mayer SA, Tarmey JJ (1996) Relationship between the volume of craniotomies for cerebral aneurysm performed at New York state hospitals and in-hospital mortality. Stroke 27: 13–17.PubMedCrossRefGoogle Scholar
  6. 6.
    Vanninen R, Koivisto T, Saari T, Hernesniemi J, Vapalahti M (1999) Ruptured intracranial aneurysms: acute endovascular treatment with electrolytically detachable coils—a prospective randomized study. Radiology 211: 325–336.PubMedGoogle Scholar
  7. 7.
    Moret J, Cognard C, Weill A, Castaings L, Rey A (1997) Reconstruction technique in the treatment of wide-neck intracranial aneurysms. Long-term angiographie and clinical results. Apropos of 56 cases. J Neuroradiol 24: 30–44.PubMedGoogle Scholar
  8. 8.
    Levy DI, Ku A (1997) Balloon-assisted coil placement in wide-necked aneurysms. Technical note. J Neurosurg 86: 724–727.PubMedCrossRefGoogle Scholar
  9. 9.
    Raftopoulos C, Mathurin P, Boscherini D, Billa RF, van Boven M, Hantson P (2000) Prospective analysis of aneurysm treatment in a series of 103 consecutive patients when endovascular embolization is considered the first option. J Neurosurg 93: 175–182.PubMedCrossRefGoogle Scholar
  10. 10.
    Johnston SC, Dudley RA, Gress DR, Ono L (1999) Surgical and endovascular treatment of unruptured cerebral aneurysms at university hospitals. Neurology 52: 1799–1805.PubMedCrossRefGoogle Scholar
  11. 11.
    Klein GE, Szolar DH, Leber KA, Karaic R, Hausegger KA (1997) Basilar tip aneurysm: endovascular treatment with Guglielmi detachable coils—midterm results. Radiology 205: 191–196.PubMedGoogle Scholar
  12. 12.
    Eskridge JM, Song JK (1998) Endovascular embolization of 150 basilar tip aneurysms with Guglielmi detachable coils: results of the Food and Drug Administration multicenter clinical trial. J Neurosurg 89: 81–86.PubMedCrossRefGoogle Scholar
  13. 13.
    Bavinzski G, Killer M, Gruber A, Reinprecht A, Gross CE, Richling B (1999) Treatment of basilar artery bifurcation aneurysms by using Guglielmi detachable coils: a 6-year experience. J Neurosurg 90: 843–852.PubMedCrossRefGoogle Scholar
  14. 14.
    Cognard C, Weill A, Castaings L, Rey A, Moret J (1998) Intracranial berry aneurysms: angiographie and clinical results after endovascular treatment. Radiology 206: 499–510.PubMedGoogle Scholar
  15. 15.
    Cognard C, Weill A, Spelle L, Piotin M, Castaings L, Rey A, Moret J (1999) Long-term angiographie follow-up of 169 intracranial berry aneurysms occluded with detachable coils. Radiology 212: 348–356.PubMedGoogle Scholar
  16. 16.
    Gurian JH, Vinuela F, Guglielmi G, Gobin YP, Duckwiler GR (1996) Endovascular embolization of superior hypophyseal artery aneurysms. Neurosurgery 39: 1150–1154.PubMedCrossRefGoogle Scholar
  17. 17.
    Roy D, Raymond J, Bouthillier A, Bojanowski MW, Moumdjian R, L’esperance G (1997) Endovascular treatment of ophthalmic segment aneurysms with Guglielmi detachable coils. AJNR 18: 1207–1215.PubMedGoogle Scholar
  18. 18.
    Vinuela F, Duckwiler G, Mawad M (1997) Guglielmi detachable coil embolization of acute intracranial aneurysm: perioperative anatomical and clinical outcome in 403 patients. J Neurosurg 86: 475–482.PubMedCrossRefGoogle Scholar
  19. 19.
    Reul J, Weis J, Spetzger U, Konert T, Fricke C, Thron A (1997) Long-term angiographic and histopathologic findings in experimental aneurysms of the carotid bifurcation embolized with platinum and tungsten coils. AJNR 18: 35–42.PubMedGoogle Scholar
  20. 20.
    Molyneux AJ, Ellison DW, Morris J, Byrne JV (1995) Histological findings in giant aneurysms treated with Guglielmi detachable coils. Report of two cases with autopsy correlation. JNeurosurg 83: 129–132.CrossRefGoogle Scholar
  21. 21.
    Mizot K, Yoshimoto T, Takahashi A, Nagamine Y (1996) A pitfall in the surgery of a recurrent aneurysm after coil embolization and its histological observation: technical case report. Neurosurgery 39: 165–168.CrossRefGoogle Scholar
  22. 22.
    Horowitz MB, Purdy PD, Burns D, Bellotto D (1997) Scanning electron microscopic findings in a basilar tip aneurysm embolized with Guglielmi detachable coils. AJNR 18: 688–690.PubMedGoogle Scholar
  23. 23.
    Shimizu S, Kurata A, Takano M, Takagi H, Yamazaki H, Miyasaka Y, Fujn K (1999) Tissue response of a small saccular aneurysm after incomplete occlusion with a Guglielmi detachable coil. AJNR 20: 546–548.Google Scholar
  24. 24.
    Castro E, Fortea F, Villoria F, Lacruz C, Ferreras B, Carrillo R (1999) Long-term histopathologic findings in two cerebral aneurysms embolized with Guglielmi detachable coils. AJNR 20: 549–552.PubMedGoogle Scholar
  25. 25.
    Graves VB, Partington CR, Rufenacht DA, Rappe AH, Strother CM (1990) Treatment of carotid artery aneurysms with platinum coils: an experimental study in dogs. AJNR 11: 249–252.PubMedGoogle Scholar
  26. 26.
    Geremia G, Haklin M, Brennecke L (1994) Embolization of experimentally created aneurysms with intravascular stent devices. AJNR 15: 1223–1231.PubMedGoogle Scholar
  27. 27.
    Feuerberg I, Lindquist C, Lindqvist M, Steiner L (1987) Natural history of postoperative aneurysm rests. J Neurosurg 66: 30–34.PubMedCrossRefGoogle Scholar
  28. 28.
    Drake CG, Allcock JM (1973) Postoperative angiography and the “slipped” clip. J Neurosurg 39: 683–689.PubMedCrossRefGoogle Scholar
  29. 29.
    Drake CG, Friedman AH, Peerless SJ (1984) Failed aneurysm surgery. Reoperation in 115 cases. J Neurosurg 61: 848–856.PubMedCrossRefGoogle Scholar
  30. 30.
    Lin T, Fox AJ, Drake CG (1989) Regrowth of aneurysm sacs from residual neck following aneurysm clipping. J Neurosurg 70: 556–560.PubMedCrossRefGoogle Scholar
  31. 31.
    Tsutsumi K, Ueki K, Usul M, Kwak S, Kirino T (1999) Risk of subarachnoid hemorrhage after surgical treatment of un-ruptured cerebral aneurysms. Stroke 30: 1181–1184.PubMedCrossRefGoogle Scholar
  32. 32.
    Graves VB, Strother CM, Duff TA, Perl J 2nd (1995) Early treatment of ruptured aneurysms with Guglielmi detachable coils: effect on subsequent bleeding. Neurosurgery 37: 640647.Google Scholar
  33. 33.
    Byrne JV, Molyneux AJ, Brennan RP, Renowden SA (1995) Embolisation of recently ruptured intracranial aneurysms. J Neurol Neurosurg Psychiatry 59: 616–620.PubMedCrossRefGoogle Scholar
  34. 34.
    Malisch TW, Guglielmi G, Vinuela F, Duckwiler. G, Gobin YP, Martin NA, Frazee JG (1997) Intracranial aneurysms treated with the Guglielmi detachable coil: midterm clinical results in a consecutive series of 100 patients. J Neurosurg 87: 176–183.Google Scholar
  35. 35.
    Raymond J, Roy D, Bojanowski M, Moumdjian R, L’esperance G (1997) Endovascular treatment of acutely ruptured and unruptured aneurysms of the basilar bifurcation. J Neurosurg 86: 211–219.PubMedCrossRefGoogle Scholar
  36. 36.
    Byrne JV, Sohn MJ, Molyneux AJ, Chir B (1999) Five-year experience in using coil embolization for ruptured intra-cranial aneurysms: outcomes and incidence of late rebleeding. J Neurosurg 90: 656–663.PubMedCrossRefGoogle Scholar
  37. 37.
    Lempert TE, Malek AM, Halbach VV, Phatouros CC, Meyers PM, Dowd CF, Higashida RT (2000) Endovascular treatment of ruptured posterior circulation cerebral aneurysms. Clinical and angiographic outcomes. Stroke 31: 100–110.PubMedCrossRefGoogle Scholar
  38. 38.
    Anonymous (1998) Unruptured intracranial aneurysms-risk of rupture and risks of surgical intervention. International Study of Unruptured Intracranial Aneurysms Investigators. N Engl J Med 339: 1725–1733.CrossRefGoogle Scholar
  39. 39.
    Baxter BW, Rosso D, Lownie SP (1998) Double micro-catheter technique for detachable coil treatment of large, wide-necked intracranial aneurysms. AJNR 19: 1176–1178.PubMedGoogle Scholar
  40. 40.
    Szikora I, Guterman LR, Wells KM, Hopkins LN (1994) Combined use of stents and coils to treat experimental wide-necked carotid aneurysms: preliminary results. AJNR 15: 1091–1102.PubMedGoogle Scholar
  41. 41.
    Mericle RA, Lanzino G, Wakhloo AK, Guterman LR, Hopkins LN (1998) Stenting and secondary coiling of intracranial internal carotid artery aneurysm: technical case report. Neurosurgery 43: 1229–1234.PubMedCrossRefGoogle Scholar
  42. 42.
    Wakhloo AK, Lanzino G,BB, Hopkins LN (1998) Stents for intracranial aneurysms: the beginning of a new endovascular era? Neurosurgery 43: 377–379.PubMedCrossRefGoogle Scholar
  43. 43.
    Wilms G, VAN Calenbergh F, Stockx L, Demaerel P, van Loon J, Goffin J (2000) Endovascular treatment of a ruptured paraclinoid aneurysm of the carotid siphon achieved using endovascular stent and endosaccular coil placement. AJNR 21: 753–756.PubMedGoogle Scholar
  44. 44.
    Ricolfi F, Le Guerinel C, Blustajn J, Combes C, Brugieres P, Melon E, Gaston A (1998) Rupture during treatment of recently ruptured aneurysms with Guglielmi electrodetachable coils. AJNR 19: 1653–1658.PubMedGoogle Scholar
  45. 45.
    Vinuela F, Duckwiler G, Mawad M (1997) Guglielmi detachable coil embolization of acute intracranial aneurysm: perioperative anatomical and clinical outcome in 403 patients. J Neurosurg 86: 475–482.PubMedCrossRefGoogle Scholar
  46. 46.
    Cronqvist M, Pierot L, Boulin A, Cognard C, Castaings L, Moret J (1998) Local intraarterial fibrinolysis of thromboemboli occurring during endovascular treatment of intracerebral aneurysm: a comparison of anatomic results and clinical outcome. AJNR 19: 157–165.PubMedGoogle Scholar
  47. 47.
    Murayama Y, Vinuela F, Duckwiler GR, Gobin YP, Guglielmi G (1999) Embolization of incidental cerebral aneurysms by using the Guglielmi detachable coil system. J Neurosurg 90: 207–214.PubMedCrossRefGoogle Scholar
  48. 48.
    Klotzsch C, Nahser HC, Henkes H, Kuhne D, Berlit P (1998) Detection of microemboli distal to cerebral aneurysms before and after therapeutic embolization. AJNR 19: 1315–1318.PubMedGoogle Scholar
  49. 49.
    Serbinenko FA (1974) Balloon catheterization and occlusion of major cerebral vessels. J Neurosurg 41: 125–145.PubMedCrossRefGoogle Scholar
  50. 50.
    Drake CG (1979) Giant intracranial aneurysms: experience with surgical treatment in 176 patients. Clin Neurosurg 26: 12–95.PubMedGoogle Scholar
  51. 51.
    Drake CG (1975) Ligation of the vertebral (unilateral or bilateral) or basilar artery in the treatment of large intracranial aneurysms. J Neurosurg 43: 255–274.PubMedCrossRefGoogle Scholar
  52. 52.
    Graves VB, Perl J 2ND, Strother CM, Wallace RC, Kesava PP, Masaryk TJ (1997) Endovascular occlusion of the carotid or vertebral artery with temporary proximal flow arrest and microcoils: clinical results. AJNR 18: 1201–1206.PubMedGoogle Scholar
  53. 53.
    Raymond J, Theron J (1986) Intracavernous aneurysms: treatment by proximal balloon occlusion of the internal carotid artery. AJNR 7:1087–1092.Google Scholar
  54. 54.
    Higashida RT, Halbach VV, Down C, Barnwell SL, Dor Mandy B, Bell J, Hieshima GB (1990) Endovascular detachable balloon embolization therapy of cavernous carotid artery aneurysms: results in 87 cases. J Neurosurg 72: 857–863.PubMedCrossRefGoogle Scholar
  55. 55.
    Fox AJ, Vinuela F, Pelz DM, Peerless SJ, Ferguson GG, Drake CG, Debrun G (1987) Use of detachable balloons for proximal artery occlusion in the treatment of unclippable cerebral aneurysms. J Neurosurg 66: 40–46.PubMedCrossRefGoogle Scholar
  56. 56.
    Berenstein A, Ransohoff J, Kupersmith M, Flamm E, Graeb D (1984) Transvascular treatment of giant aneurysms of the cavernous carotid and vertebral arteries. Functional investigation and embolization. Surg Neurol 21: 3–12.PubMedCrossRefGoogle Scholar
  57. 57.
    Vazquez Anon V, Aymard A, Gobin YP, Casasco A, Ruffenacht D, Khayata MH, Abizanda E, Redondo A, Merland JJ (1992) Balloon occlusion of the internal carotid artery in 40 cases of giant intracavernous aneurysm: technical aspects, cerebral monitoring, and results. Neuroradiology 34: 245–251.CrossRefGoogle Scholar
  58. 58.
    Bavinzski G, Killer M, Ferraz-Leite H, Gruber A, Gross CE, Richling B (1998) Endovascular therapy of idiopathic cavernous aneurysms over 11 years. AJNR 19: 559–565.PubMedGoogle Scholar
  59. 59.
    Taki W, Nishi S, Yamashita K, Sadatoh A, Nakahara I, Kikuchi H, Iwata H (1992) Selection and combination of various endovascular techniques in the treatment of giant aneurysms. J Neurosurg 77:37–42.Google Scholar
  60. 60.
    Higashida RT, Halbach VV, Dowd CF, Barnwell SL, Hieshima GB (1991) Intracranial aneurysms: interventional neurovascular treatment with detachable balloons-results in 215 cases. Radiology 178: 663–670.PubMedGoogle Scholar
  61. 61.
    Halbach VV, Higashida RT, Dowd CF, Fraser KW, Smith TP, Teitelbaum GP, Wilson CB, Hieshima GB (1993) Endovascular treatment of vertebral artery dissections and pseudo aneurysms. J Neurosurg 79: 183–191.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Pearse Morris
    • 1
  1. 1.School of MedicineWake Forest UniversityWinston-SalemUSA

Personalised recommendations