Tumor Embolization
Abstract
The techniques and principles of embolization of preoperative meningiomas can be generalized to all vascular tumors of the skull base. Although the techniques of preoperative devascularization of vascular tumors of the head and neck have been established for many years, the role of interventional neuroradiology in this arena is still limited to a relatively small number of patients. While it is known that presurgical embolization of meningiomas brings greater ease of surgery in a cost-effective manner, reduced perioperative blood loss, and possibly diminished likelihood of tumor recurrence,1 the proportion of head and neck tumors suitable for this type of procedure is still the minority. However, a greater role for interventional neuroradiology may evolve in the future with treatment protocols using highly selective infusions of high-dose chemotherapy for squamous carcinoma and other tumors of head and neck.
Keywords
Internal Carotid Artery Vertebral Artery Ophthalmic Artery Middle Meningeal Artery Preoperative EmbolizationPreview
Unable to display preview. Download preview PDF.
References
- 1.Dean BL, Flom RA, Wallace RC, Khayata MH, Obuchowski NA, HodakJA, ZabramskiJM, SpetzlerRF (1994) Efficacy of endovascular treatment of meningiomas: evaluation with matched samples. AJNR 15: 1675–1680.PubMedGoogle Scholar
- 2.AhujaA, GibbonsKJ (1994) Endovascular therapy of central nervous system tumors. Review, 68 refs. Neurosurg Clin North Am 5: 541–554.Google Scholar
- 3.TeradaT, KinoshitaY, YokoteH, TsuuraM, ItakuraT, KomaiN, NakamuraY, TanakaS, KuriyamaT (1996) Preoperative embolization of meningiomas fed by ophthalmic branch arteries. Surg Neurol 45: 161–166.PubMedCrossRefGoogle Scholar
- 4.NelsonPK, SettonA, ChoiIS, RansohoffJ, BerensteinA (1994) Current status of interventional neuroradiology in the management of meningiomas. Neurosurg Clin North Am 5: 235–259.Google Scholar
- 5.MorrisPP (1999) Interventional neuroradiology in the treatment of brain tumors. Neuroimag Clin NA 9: 767–778.Google Scholar
- 6.LasjauniasP, BerensteinA (1987) in Surgical Neuroangiography. Vol. 2. Berlin-Heidelberg-New York: Springer-Verlag.Google Scholar
- 7.WakhlooAK, JuenglingFD, VAN VelthovenV, SchumacherM, HennigJ, SchwechheimerK (1993) Extended preoperative polyvinyl alcohol microembolization of intracranial meningiomas: assessment of two embolization techniques. AJNR 14: 571–582.PubMedGoogle Scholar
- 8.GrandC, BankWO, BaleriauxD, MatosC, DewitteO, BrotchiJ, DelcourC (1993) Gadolinium-enhanced MR in the evaluation of preoperative meningioma embolization. AJNR 14: 563–569.PubMedGoogle Scholar
- 9.BerettaL, Dell’acqua A, GiorgiE, NapolitanoL, TommasinoC, RighiC, FerrariDA PassanoC, MottiE (1992) Complications during preoperative embolization in in- tracranial meningioma. Minerva Anestesiologica 58: 111–114.PubMedGoogle Scholar
- 10.KallmesDF, EvansAJ, KaptainGJ, MathisJM, JensenME, JaneJA, DionJE (1997) Hemorrhagic complications in embolization of a meningioma: case report and review of the literature. Neuroradiology 39: 877–880.PubMedCrossRefGoogle Scholar
- 11.HayashiT, ShojimaK, UtsunomiyaH, MoritakaK, HondaE (1987) Subarachnoid hemorrhage after preoperative em- bolization of a cystic meningioma. Surg Neurol 27: 295–300.PubMedCrossRefGoogle Scholar
- 12.SuyamaT, Tamaki N, FujiwaraK, HamanoS, KimuraM,MatsumotoS (1987) Peritumoral and intratumoral hemorrhage after gelatin sponge embolization of malignant meningioma: case report. Neurosurgery 21: 944–946.Google Scholar
- 13.TeradaT, KinoshitaY, YokoteH, TsuuraM, ItakuraT, KomaiN, NakamuraY, TanakaS, KuriyamaT (1996) Preoperative embolization of meningiomas fed by ophthalmic branch arteries. Surg Neurol 45: 161–166.PubMedCrossRefGoogle Scholar
- 14.TeradaT, NakaiE, TsumotoT, ItakuraT (1997) latrogenic arteriovenous fistula of the middle meningeal artery caused during embolization for meningioma-case report. Neurologia Medico-Chirurgica 37: 677–680.Google Scholar
- 15.CasascoA, HerbreteauD, HoudartE, GeorgeB, HuyTB, DeffresneD, MerlandJJ (1994) Devascularization of craniofacial tumors by percutaneous tumor puncture. AJNR 15: 1233–1239.PubMedGoogle Scholar
- 16.CasascoA, HoudartE, BiondiA, JhaveriHS, HerbreteauD, AymardA, MerlandJJ (1999) Major complications of percutaneous embolization of skull-base tumors. AJNR 20: 179–181.PubMedGoogle Scholar
- 17.SiniluotoTM, LuotonenJP, TikkakoskiTA, LeinonenAS, JokinenKE (1993) Value of preoperative embolization in surgery for nasopharyngeal angiofibroma. J Laryngol Otol 107: 514–521.PubMedCrossRefGoogle Scholar
- 18.MccombeA, LundVJ, HowardDJ (1990) Recurrence in juvenile angiofibroma. Rhinology 28: 97–102.PubMedGoogle Scholar
- 19.SchrothG, HaldemannAR, MarianiL, RemondaL, RavehJ (1996) Preoperative embolization of paragangliomas and angiofibromas. Measurement of intratumoral arteriovenous shunts. Arch Otolaryngol Head Neck Surg 122: 1320–1325.Google Scholar
- 20.YoungNM, WietRJ, RussellEJ, MonsellEM (1988) Superselective embolization of glomus jugulare tumors. Ann Otol Rhinol Laryngol 97: 613–620.PubMedGoogle Scholar
- 21.TranBA HuyP, DeffrennesD, BretteMD, GeorgeB, ThurelC, GelbertF, MerlandJJ, WassefM (1987) Tympanic and jugular paragangliomas. II. Angiographie, surgical and irradiation treatment. Results. Indications. Apropos of 25 cases. Annales de Oto-Laryngologie et de Chirurgie Cervico-Faciale 104: 489–499.Google Scholar
- 22.FruhwirthJ, KochG, KleinGE (1996) Preoperative angiographie embolization of carotid glomus tumors. A method for improving operability. HNO 44: 510–513.PubMedCrossRefGoogle Scholar
- 23.MurphyTP, Brackmann DE (1989) Effects of preoperative embolization on glomus jugulare tumors. Laryngoscope 99: 1244–1247.PubMedCrossRefGoogle Scholar
- 24.HeadmanRC, GillespieJE, RamsdenRT (1993) Facial palsy after glomus tumour embolization. J Laryngol Otol 107: 963–966.Google Scholar
- 25.MarangosN, SchumacherM (1999) Facial palsy after glomus jugulare tumour embolization. J Laryngol Otol 113: 268–270.PubMedCrossRefGoogle Scholar
- 26.MatishakMZ, SymonL, CheesemanA, PamphlettR (1987)Catecholamine-secreting paragangliomas of the base of the skull. Report of two cases. J Neurosurg 66: 604–608.Google Scholar
- 27.KremerR, MichelRP, PosnerB, WangNS, LafondGP, CrawhallJC (1989) Catecholamine-secreting paraganglioma of glomus jugulare region. Am J Med Sci 297: 46–48.PubMedCrossRefGoogle Scholar
- 28.MukherjiSK, CastilloM (1996) Adenocarcinoma of the endolymphatic sac: imaging features and preoperative embolization. Neuroradiology 38: 179–180.PubMedCrossRefGoogle Scholar
- 29.EhrlichP (1906) Collected Studies in Immunity. New York: John Wiley, 567–595.Google Scholar
- 30.RapoportSI, RobinsonPJ (1986) Tight-junctional modification as the basis of osmotic opening of the blood-brain barrier. Ann NYAcad Sci 481: 250–267.Google Scholar
- 31.KrollRA, NeuweltEA (1998) Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means. Neurosurgery 42: 1083–1099.PubMedCrossRefGoogle Scholar
- 32.McallisterLD, DoolittleND, GuastadisegniPE, KraemerDF, LacyCA, GrossenJR, NeuweltEA (2000) Cogni-tive outcomes and longterm followup results after enhanced chemotherapy delivery for primary central nervous system lymphoma. Neurosurgery 46: 51–61.PubMedCrossRefGoogle Scholar
- 33.ElliottPJ, HaywardNJ, HuffMR, NagleTL, BlackKL, BartusRT (1996) Unlocking the blood-brain barrier: a role for RMP-7 in brain tumor therapy. Experimental Neurol 141: 214–224.CrossRefGoogle Scholar
- 34.DahlborgSA, HennerWD, GrossenJR, TablemanM, PetrilloA, BrazielR, Neuweelt EA (1996) Non-AIDS primary CNS lymphoma: first example of a durable response in a primary brain tumor using enhanced chemotherapy delivery without cognitive loss and without radiotherapy. Cancer J Sci Am 2: 166–174.PubMedGoogle Scholar
- 35.DahlborgSA, PetrilloA, GrossenJRRoman-Goldstein S, DoolittleND, FullerKH, NeuweltEA (1998) The potential for complete and durable response in non-glial primary brain tumors in children and young adults with enhanced chemotherapy delivery. Cancer J Sci Am 4: 110–124.PubMedGoogle Scholar
- 36.BlackKL, BabaT, PardridgeWM (1994) Enzymatic barrier protects brain capillaries from leukotriene C4. J Neurosurg 81: 745–751.PubMedCrossRefGoogle Scholar
- 37.BlackKL, KingWA, IkezakeK (1990) Selective opening of the blood-brain barrier by intracarotid infusion of leukotriene C4. J Neurosurg 72: 912–916.PubMedCrossRefGoogle Scholar
- 38.InamuraT, BlackKL (1994) Bradykinin selectively opens blood-tumor barrier in experimental brain tumors. J Cereb Blood Flow Metabol 14: 862–870.CrossRefGoogle Scholar
- 39.InamuraT, NomuraT, IkezakiK, FukuiM, PollingerG,BlackKL (1994) Intracarotid histamine infusion increases blood tumor permeability in RG2 glioma. Neurol Res 16: 125–128.Google Scholar
- 40.InamuraT, NomuraT, BartusRT, BlackKL (1994) Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors. J Neurosurg 81: 752–758.PubMedCrossRefGoogle Scholar
- 41.ElferinkF, Van Der Vijgh WJ, KleinI, PinedoHM (1986)Interaction of cisplatin and carboplatin with sodium thiosulfate: reaction rates and protein binding. Clin Chem 32: 641–645.Google Scholar
- 42.NakanoS, MatsukadoK, BlackKL (1996) Increased brain tumor microvessel permeability after intracarotid bradykinin infusion is mediated by nitric oxide. Cancer Res 56: 4027–4031.PubMedGoogle Scholar
- 43.MatsukadoK, InamuraT, NakanoS, FukuiM, BartusRT,BlackKL (1996) Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7. Neurosurgery 39: 125–133.Google Scholar
- 44.MatsukadoK, NakanoS, BartusRT, BlackKL (1997)Steroids decrease uptake of carboplatin in rat gliomasuptake improved by intracarotid infusion of bradykinin analog, RMP-7. J Neuro-Oncol 34: 131–138.Google Scholar
- 45.FireJR, GobbelGT, MesiwalaAH, ShinHJ, NakagawaM, LambornKR, SeihanTM, ElliottPJ (1998) Cerebrovascular effect of the bradykinin analog RMP-7 in normal and irradiated dog brain. J Neuro-Oncol 37: 199–215.CrossRefGoogle Scholar
- 46.RileyMG, KimNN, WatsonV, GobinYP, LebelCP, BlackKL, BartusRT (1998) Intra-arterial administration of carboplatin and the blood brain barrier permeabilizing agent, RMP-7: a toxicologic evaluation in swine. J Neuro-Oncol 36: 167–178.CrossRefGoogle Scholar
- 47.KogaH, InamuraT, IkezakiK, NomuraT, SamotoK, FujuiM (1996) Increased delivery of a new cisplatin analogue (254-S) in a rat brain tumor by intracarotid infusion of bradykinin. Neurol Res 18: 244–247.PubMedGoogle Scholar
- 48.WuHM, LeeAG, LehaneDE, ChiTL, LewisRA (1997) Ocular and orbital complications of intraarterial cisplatin. A case report. J Neuro-Ophthalmol 17: 195–198.CrossRefGoogle Scholar
- 49.MillayRH, KleinML, ShultsWT, DahlborgSA, NeuweltEA (1986) Maculopathy associated with combination chemotherapy and osmotic opening of the blood-brain barrier. Am J Ophthalmol 102: 626–632.PubMedGoogle Scholar
- 50.AldersonLM, NoonanPT, ChoiIS, HensonJW (1996) Regional subacute cranial neuropathies following internal carotid cisplatin infusion. Neurology 47: 1088–1090.PubMedCrossRefGoogle Scholar
- 51.CloughesyTF, BlackKL, GobinYP, FarahaniK, NelsonG, VillablancaP, KabbinavarF, VineulaF, WortelCH (1999)Intra-arterial Cereport (RMP-7) and carboplatin: a dose escalation study for recurrent malignant gliomas. Neurosurgery 44: 270–278.Google Scholar
- 52.CloughesyTF, GobinTP, BlackKL, VinuelaF, TaftF, KadkhodaB, KanninavarF (1997) Intra-arterial carboplatin chemotherapy for brain tumors: a dose escalation study based on cerebral blood flow. J Neuro-Oncol 35: 121–131.CrossRefGoogle Scholar
- 53.AssiettiR, OlsonJJ (1996) Intra-arterial cisplatin in malignant brain tumors: incidence and severity of otic toxicity. J Neuro-Oncol 27: 251–258.CrossRefGoogle Scholar
- 54.WilliamsPC, HennerWD, Roman-Goldstein S, DahlborgSA, BrummettRE, TablemanM, DanaBW, NeuweltEA (1995) Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms. Neurosurgery 37: 17–27.PubMedCrossRefGoogle Scholar
- 55.WetmoreSJ, KoikeKJ, BloomfieldSM (1997) Profound hearing loss from intravertebral artery cisplatin. Otolaryngol Head Neck Surg 116: 234–237.PubMedCrossRefGoogle Scholar
- 56.NeuweltEA, BrummettRE, RemsenLG, KrollRA, PagelMA, MccormickCI, GuitjensS, MuldoonLL (1996) In vitro and animal studies of sodium thiosulfate as a potential chemoprotectant against carboplatin-induced ototoxicity. Cancer Res 56: 706–709.PubMedGoogle Scholar
- 57.PfeifleCE, HowellSB, FelthouseRD, WoliverTB, AndrewsPA, MarkmanM, MurphyMP (1985) High-dose cisplatin with sodium thiosulfate protection. J Clin Oncol 3: 237–244.PubMedGoogle Scholar
- 58.RobbinsKT, StornioloAM, KerberC, SeagrenS, BersonA, HowellSB (1992) Rapid superselective high-dose cisplatin infusion for advanced head and neck malignancies. Head Neck 14: 364–371.PubMedCrossRefGoogle Scholar
- 59.LosG, BlommaertFA, BartonR, HeathDD, Den EngelseL, HanchettC, SB (1995) Selective intra-arterial infusion of high-dose cisplatin in patients with advanced head and neck cancer results in high tumor platinum concentrations and cisplatin-DNA adduct formation. Cancer Chemother Pharmacol 37: 150–154.Google Scholar
- 60.KerberCW, WongWH, HowellSB, HanchettK, RobbinsKT (1998) An organ-preserving selective arterial chemother-apy strategy for head and neck cancer. AJNR 19: 935–941.PubMedGoogle Scholar
- 61.MadasuR, RuckensteinMJ, LeakeF, SteereE, RobbinsKT(1997) Ototoxic effects of supradose cisplatin with sodium thiosulfate neutralization in patients with head and neck Arch Otolaryngol Head Neck Surg 123: 978–981.Google Scholar
- 62.WeismanRA, ChristenRD, JonesVE, KerberCW, Seagren OrloffLA, GlassmeyerSL, HowellSB, RobbinsKT (1998) Observations on control of N2 and N3 neck disease in squamous cell carcinoma of the head and neck by intraarterial chemoradiation. Laryngoscope 108: 800–805.Google Scholar