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Tumor Embolization

  • Pearse Morris
Chapter

Abstract

The techniques and principles of embolization of preoperative meningiomas can be generalized to all vascular tumors of the skull base. Although the techniques of preoperative devascularization of vascular tumors of the head and neck have been established for many years, the role of interventional neuroradiology in this arena is still limited to a relatively small number of patients. While it is known that presurgical embolization of meningiomas brings greater ease of surgery in a cost-effective manner, reduced perioperative blood loss, and possibly diminished likelihood of tumor recurrence,1 the proportion of head and neck tumors suitable for this type of procedure is still the minority. However, a greater role for interventional neuroradiology may evolve in the future with treatment protocols using highly selective infusions of high-dose chemotherapy for squamous carcinoma and other tumors of head and neck.

Keywords

Internal Carotid Artery Vertebral Artery Ophthalmic Artery Middle Meningeal Artery Preoperative Embolization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. 1.
    Dean BL, Flom RA, Wallace RC, Khayata MH, Obuchowski NA, HodakJA, ZabramskiJM, SpetzlerRF (1994) Efficacy of endovascular treatment of meningiomas: evaluation with matched samples. AJNR 15: 1675–1680.PubMedGoogle Scholar
  2. 2.
    AhujaA, GibbonsKJ (1994) Endovascular therapy of central nervous system tumors. Review, 68 refs. Neurosurg Clin North Am 5: 541–554.Google Scholar
  3. 3.
    TeradaT, KinoshitaY, YokoteH, TsuuraM, ItakuraT, KomaiN, NakamuraY, TanakaS, KuriyamaT (1996) Preoperative embolization of meningiomas fed by ophthalmic branch arteries. Surg Neurol 45: 161–166.PubMedCrossRefGoogle Scholar
  4. 4.
    NelsonPK, SettonA, ChoiIS, RansohoffJ, BerensteinA (1994) Current status of interventional neuroradiology in the management of meningiomas. Neurosurg Clin North Am 5: 235–259.Google Scholar
  5. 5.
    MorrisPP (1999) Interventional neuroradiology in the treatment of brain tumors. Neuroimag Clin NA 9: 767–778.Google Scholar
  6. 6.
    LasjauniasP, BerensteinA (1987) in Surgical Neuroangiography. Vol. 2. Berlin-Heidelberg-New York: Springer-Verlag.Google Scholar
  7. 7.
    WakhlooAK, JuenglingFD, VAN VelthovenV, SchumacherM, HennigJ, SchwechheimerK (1993) Extended preoperative polyvinyl alcohol microembolization of intracranial meningiomas: assessment of two embolization techniques. AJNR 14: 571–582.PubMedGoogle Scholar
  8. 8.
    GrandC, BankWO, BaleriauxD, MatosC, DewitteO, BrotchiJ, DelcourC (1993) Gadolinium-enhanced MR in the evaluation of preoperative meningioma embolization. AJNR 14: 563–569.PubMedGoogle Scholar
  9. 9.
    BerettaL, Dell’acqua A, GiorgiE, NapolitanoL, TommasinoC, RighiC, FerrariDA PassanoC, MottiE (1992) Complications during preoperative embolization in in- tracranial meningioma. Minerva Anestesiologica 58: 111–114.PubMedGoogle Scholar
  10. 10.
    KallmesDF, EvansAJ, KaptainGJ, MathisJM, JensenME, JaneJA, DionJE (1997) Hemorrhagic complications in embolization of a meningioma: case report and review of the literature. Neuroradiology 39: 877–880.PubMedCrossRefGoogle Scholar
  11. 11.
    HayashiT, ShojimaK, UtsunomiyaH, MoritakaK, HondaE (1987) Subarachnoid hemorrhage after preoperative em- bolization of a cystic meningioma. Surg Neurol 27: 295–300.PubMedCrossRefGoogle Scholar
  12. 12.
    SuyamaT, Tamaki N, FujiwaraK, HamanoS, KimuraM,MatsumotoS (1987) Peritumoral and intratumoral hemorrhage after gelatin sponge embolization of malignant meningioma: case report. Neurosurgery 21: 944–946.Google Scholar
  13. 13.
    TeradaT, KinoshitaY, YokoteH, TsuuraM, ItakuraT, KomaiN, NakamuraY, TanakaS, KuriyamaT (1996) Preoperative embolization of meningiomas fed by ophthalmic branch arteries. Surg Neurol 45: 161–166.PubMedCrossRefGoogle Scholar
  14. 14.
    TeradaT, NakaiE, TsumotoT, ItakuraT (1997) latrogenic arteriovenous fistula of the middle meningeal artery caused during embolization for meningioma-case report. Neurologia Medico-Chirurgica 37: 677–680.Google Scholar
  15. 15.
    CasascoA, HerbreteauD, HoudartE, GeorgeB, HuyTB, DeffresneD, MerlandJJ (1994) Devascularization of craniofacial tumors by percutaneous tumor puncture. AJNR 15: 1233–1239.PubMedGoogle Scholar
  16. 16.
    CasascoA, HoudartE, BiondiA, JhaveriHS, HerbreteauD, AymardA, MerlandJJ (1999) Major complications of percutaneous embolization of skull-base tumors. AJNR 20: 179–181.PubMedGoogle Scholar
  17. 17.
    SiniluotoTM, LuotonenJP, TikkakoskiTA, LeinonenAS, JokinenKE (1993) Value of preoperative embolization in surgery for nasopharyngeal angiofibroma. J Laryngol Otol 107: 514–521.PubMedCrossRefGoogle Scholar
  18. 18.
    MccombeA, LundVJ, HowardDJ (1990) Recurrence in juvenile angiofibroma. Rhinology 28: 97–102.PubMedGoogle Scholar
  19. 19.
    SchrothG, HaldemannAR, MarianiL, RemondaL, RavehJ (1996) Preoperative embolization of paragangliomas and angiofibromas. Measurement of intratumoral arteriovenous shunts. Arch Otolaryngol Head Neck Surg 122: 1320–1325.Google Scholar
  20. 20.
    YoungNM, WietRJ, RussellEJ, MonsellEM (1988) Superselective embolization of glomus jugulare tumors. Ann Otol Rhinol Laryngol 97: 613–620.PubMedGoogle Scholar
  21. 21.
    TranBA HuyP, DeffrennesD, BretteMD, GeorgeB, ThurelC, GelbertF, MerlandJJ, WassefM (1987) Tympanic and jugular paragangliomas. II. Angiographie, surgical and irradiation treatment. Results. Indications. Apropos of 25 cases. Annales de Oto-Laryngologie et de Chirurgie Cervico-Faciale 104: 489–499.Google Scholar
  22. 22.
    FruhwirthJ, KochG, KleinGE (1996) Preoperative angiographie embolization of carotid glomus tumors. A method for improving operability. HNO 44: 510–513.PubMedCrossRefGoogle Scholar
  23. 23.
    MurphyTP, Brackmann DE (1989) Effects of preoperative embolization on glomus jugulare tumors. Laryngoscope 99: 1244–1247.PubMedCrossRefGoogle Scholar
  24. 24.
    HeadmanRC, GillespieJE, RamsdenRT (1993) Facial palsy after glomus tumour embolization. J Laryngol Otol 107: 963–966.Google Scholar
  25. 25.
    MarangosN, SchumacherM (1999) Facial palsy after glomus jugulare tumour embolization. J Laryngol Otol 113: 268–270.PubMedCrossRefGoogle Scholar
  26. 26.
    MatishakMZ, SymonL, CheesemanA, PamphlettR (1987)Catecholamine-secreting paragangliomas of the base of the skull. Report of two cases. J Neurosurg 66: 604–608.Google Scholar
  27. 27.
    KremerR, MichelRP, PosnerB, WangNS, LafondGP, CrawhallJC (1989) Catecholamine-secreting paraganglioma of glomus jugulare region. Am J Med Sci 297: 46–48.PubMedCrossRefGoogle Scholar
  28. 28.
    MukherjiSK, CastilloM (1996) Adenocarcinoma of the endolymphatic sac: imaging features and preoperative embolization. Neuroradiology 38: 179–180.PubMedCrossRefGoogle Scholar
  29. 29.
    EhrlichP (1906) Collected Studies in Immunity. New York: John Wiley, 567–595.Google Scholar
  30. 30.
    RapoportSI, RobinsonPJ (1986) Tight-junctional modification as the basis of osmotic opening of the blood-brain barrier. Ann NYAcad Sci 481: 250–267.Google Scholar
  31. 31.
    KrollRA, NeuweltEA (1998) Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means. Neurosurgery 42: 1083–1099.PubMedCrossRefGoogle Scholar
  32. 32.
    McallisterLD, DoolittleND, GuastadisegniPE, KraemerDF, LacyCA, GrossenJR, NeuweltEA (2000) Cogni-tive outcomes and longterm followup results after enhanced chemotherapy delivery for primary central nervous system lymphoma. Neurosurgery 46: 51–61.PubMedCrossRefGoogle Scholar
  33. 33.
    ElliottPJ, HaywardNJ, HuffMR, NagleTL, BlackKL, BartusRT (1996) Unlocking the blood-brain barrier: a role for RMP-7 in brain tumor therapy. Experimental Neurol 141: 214–224.CrossRefGoogle Scholar
  34. 34.
    DahlborgSA, HennerWD, GrossenJR, TablemanM, PetrilloA, BrazielR, Neuweelt EA (1996) Non-AIDS primary CNS lymphoma: first example of a durable response in a primary brain tumor using enhanced chemotherapy delivery without cognitive loss and without radiotherapy. Cancer J Sci Am 2: 166–174.PubMedGoogle Scholar
  35. 35.
    DahlborgSA, PetrilloA, GrossenJRRoman-Goldstein S, DoolittleND, FullerKH, NeuweltEA (1998) The potential for complete and durable response in non-glial primary brain tumors in children and young adults with enhanced chemotherapy delivery. Cancer J Sci Am 4: 110–124.PubMedGoogle Scholar
  36. 36.
    BlackKL, BabaT, PardridgeWM (1994) Enzymatic barrier protects brain capillaries from leukotriene C4. J Neurosurg 81: 745–751.PubMedCrossRefGoogle Scholar
  37. 37.
    BlackKL, KingWA, IkezakeK (1990) Selective opening of the blood-brain barrier by intracarotid infusion of leukotriene C4. J Neurosurg 72: 912–916.PubMedCrossRefGoogle Scholar
  38. 38.
    InamuraT, BlackKL (1994) Bradykinin selectively opens blood-tumor barrier in experimental brain tumors. J Cereb Blood Flow Metabol 14: 862–870.CrossRefGoogle Scholar
  39. 39.
    InamuraT, NomuraT, IkezakiK, FukuiM, PollingerG,BlackKL (1994) Intracarotid histamine infusion increases blood tumor permeability in RG2 glioma. Neurol Res 16: 125–128.Google Scholar
  40. 40.
    InamuraT, NomuraT, BartusRT, BlackKL (1994) Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors. J Neurosurg 81: 752–758.PubMedCrossRefGoogle Scholar
  41. 41.
    ElferinkF, Van Der Vijgh WJ, KleinI, PinedoHM (1986)Interaction of cisplatin and carboplatin with sodium thiosulfate: reaction rates and protein binding. Clin Chem 32: 641–645.Google Scholar
  42. 42.
    NakanoS, MatsukadoK, BlackKL (1996) Increased brain tumor microvessel permeability after intracarotid bradykinin infusion is mediated by nitric oxide. Cancer Res 56: 4027–4031.PubMedGoogle Scholar
  43. 43.
    MatsukadoK, InamuraT, NakanoS, FukuiM, BartusRT,BlackKL (1996) Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7. Neurosurgery 39: 125–133.Google Scholar
  44. 44.
    MatsukadoK, NakanoS, BartusRT, BlackKL (1997)Steroids decrease uptake of carboplatin in rat gliomasuptake improved by intracarotid infusion of bradykinin analog, RMP-7. J Neuro-Oncol 34: 131–138.Google Scholar
  45. 45.
    FireJR, GobbelGT, MesiwalaAH, ShinHJ, NakagawaM, LambornKR, SeihanTM, ElliottPJ (1998) Cerebrovascular effect of the bradykinin analog RMP-7 in normal and irradiated dog brain. J Neuro-Oncol 37: 199–215.CrossRefGoogle Scholar
  46. 46.
    RileyMG, KimNN, WatsonV, GobinYP, LebelCP, BlackKL, BartusRT (1998) Intra-arterial administration of carboplatin and the blood brain barrier permeabilizing agent, RMP-7: a toxicologic evaluation in swine. J Neuro-Oncol 36: 167–178.CrossRefGoogle Scholar
  47. 47.
    KogaH, InamuraT, IkezakiK, NomuraT, SamotoK, FujuiM (1996) Increased delivery of a new cisplatin analogue (254-S) in a rat brain tumor by intracarotid infusion of bradykinin. Neurol Res 18: 244–247.PubMedGoogle Scholar
  48. 48.
    WuHM, LeeAG, LehaneDE, ChiTL, LewisRA (1997) Ocular and orbital complications of intraarterial cisplatin. A case report. J Neuro-Ophthalmol 17: 195–198.CrossRefGoogle Scholar
  49. 49.
    MillayRH, KleinML, ShultsWT, DahlborgSA, NeuweltEA (1986) Maculopathy associated with combination chemotherapy and osmotic opening of the blood-brain barrier. Am J Ophthalmol 102: 626–632.PubMedGoogle Scholar
  50. 50.
    AldersonLM, NoonanPT, ChoiIS, HensonJW (1996) Regional subacute cranial neuropathies following internal carotid cisplatin infusion. Neurology 47: 1088–1090.PubMedCrossRefGoogle Scholar
  51. 51.
    CloughesyTF, BlackKL, GobinYP, FarahaniK, NelsonG, VillablancaP, KabbinavarF, VineulaF, WortelCH (1999)Intra-arterial Cereport (RMP-7) and carboplatin: a dose escalation study for recurrent malignant gliomas. Neurosurgery 44: 270–278.Google Scholar
  52. 52.
    CloughesyTF, GobinTP, BlackKL, VinuelaF, TaftF, KadkhodaB, KanninavarF (1997) Intra-arterial carboplatin chemotherapy for brain tumors: a dose escalation study based on cerebral blood flow. J Neuro-Oncol 35: 121–131.CrossRefGoogle Scholar
  53. 53.
    AssiettiR, OlsonJJ (1996) Intra-arterial cisplatin in malignant brain tumors: incidence and severity of otic toxicity. J Neuro-Oncol 27: 251–258.CrossRefGoogle Scholar
  54. 54.
    WilliamsPC, HennerWD, Roman-Goldstein S, DahlborgSA, BrummettRE, TablemanM, DanaBW, NeuweltEA (1995) Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms. Neurosurgery 37: 17–27.PubMedCrossRefGoogle Scholar
  55. 55.
    WetmoreSJ, KoikeKJ, BloomfieldSM (1997) Profound hearing loss from intravertebral artery cisplatin. Otolaryngol Head Neck Surg 116: 234–237.PubMedCrossRefGoogle Scholar
  56. 56.
    NeuweltEA, BrummettRE, RemsenLG, KrollRA, PagelMA, MccormickCI, GuitjensS, MuldoonLL (1996) In vitro and animal studies of sodium thiosulfate as a potential chemoprotectant against carboplatin-induced ototoxicity. Cancer Res 56: 706–709.PubMedGoogle Scholar
  57. 57.
    PfeifleCE, HowellSB, FelthouseRD, WoliverTB, AndrewsPA, MarkmanM, MurphyMP (1985) High-dose cisplatin with sodium thiosulfate protection. J Clin Oncol 3: 237–244.PubMedGoogle Scholar
  58. 58.
    RobbinsKT, StornioloAM, KerberC, SeagrenS, BersonA, HowellSB (1992) Rapid superselective high-dose cisplatin infusion for advanced head and neck malignancies. Head Neck 14: 364–371.PubMedCrossRefGoogle Scholar
  59. 59.
    LosG, BlommaertFA, BartonR, HeathDD, Den EngelseL, HanchettC, SB (1995) Selective intra-arterial infusion of high-dose cisplatin in patients with advanced head and neck cancer results in high tumor platinum concentrations and cisplatin-DNA adduct formation. Cancer Chemother Pharmacol 37: 150–154.Google Scholar
  60. 60.
    KerberCW, WongWH, HowellSB, HanchettK, RobbinsKT (1998) An organ-preserving selective arterial chemother-apy strategy for head and neck cancer. AJNR 19: 935–941.PubMedGoogle Scholar
  61. 61.
    MadasuR, RuckensteinMJ, LeakeF, SteereE, RobbinsKT(1997) Ototoxic effects of supradose cisplatin with sodium thiosulfate neutralization in patients with head and neck Arch Otolaryngol Head Neck Surg 123: 978–981.Google Scholar
  62. 62.
    WeismanRA, ChristenRD, JonesVE, KerberCW, Seagren OrloffLA, GlassmeyerSL, HowellSB, RobbinsKT (1998) Observations on control of N2 and N3 neck disease in squamous cell carcinoma of the head and neck by intraarterial chemoradiation. Laryngoscope 108: 800–805.Google Scholar

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© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Pearse Morris
    • 1
  1. 1.School of MedicineWake Forest UniversityWinston-SalemUSA

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