Nonepithelial tumors such as those of lymphoid tissue, soft tissue, bone, and cartilage are not included
  • American Joint Committee on Cancer

Summary of Changes

T4 lesions have been divided into T4a (resectable) and T4b (unresectable), leading to the division of Stage IV into Stage IVA, Stage IVB, and Stage IVC.


Squamous Cell Carcinoma Basal Cell Carcinoma American Joint Committee Adenoid Cystic Carcinoma Pleomorphic Adenoma 
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  1. Archer CR, Yeager VL, Herbold DR: CT versus histology of laryngeal cancer: the value in predicting laryngeal cartilage invasion. Laryngoscope 93:140–147, 1983PubMedCrossRefGoogle Scholar
  2. Cooper JS, Farnan NC, Asbell SO, et al: Recursive partitioning analysis of 2,105 patients treated in Radiation Therapy Oncology Group studies of head and neck cancer. Cancer 77:1905–1911, 1996PubMedCrossRefGoogle Scholar
  3. Deleyiannis FW, Thomas DB, Vaughan TL, et al: Alcoholism: independent predictor of survival in patients with head and neck cancer. J Natl Cancer Inst 88:542–549, 1996PubMedCrossRefGoogle Scholar
  4. Eibaud JD, Elias EG, Suter CM, et al: Prognostic factors in squamous cell carcinoma of the larynx. Am J Surg 58:314–317, 1989Google Scholar
  5. Faye-Lund H, Abdelnoor M: Prognostic factors of survival in a cohort of head and neck cancer patients in Oslo. Eur J Cancer B Oral Oncol 2:83–90, 1996CrossRefGoogle Scholar
  6. Isaacs JJ, Mancuso AA, Mendenhall WM, et al: Deep spread patterns in CT staging of t2–4 squamous cell laryngeal carcinoma. Otolaryngol Head Neck Surg 99:455–464, 1988PubMedGoogle Scholar
  7. Kaplan MH, Feinstein AR: The importance of classifying initial co-morbidity in evaluating the outcome of diabetes mellitus. J Chron Dis 37:387–404, 1974CrossRefGoogle Scholar
  8. Karnofsky DA, Abelman WH, Craver LF, Burchenal JH: The use of nitrogen mustards in the palliative treatment of carcinoma. Cancer 1:634–656, 1948CrossRefGoogle Scholar
  9. Mafee MF, Schieid JA, Valvassori GE, et al: CT of the larynx: correlation with anatomic and pathologic studies in cases of laryngeal carcinoma. Radiology 147:123–128, 1983PubMedGoogle Scholar
  10. Mendenhall WM, Parsons JT, Stringer SP, et al: Carcinoma of the supraglottic larynx: a basis for comparing the results of radiotherapy and surgery. Head Neck 12:204–209, 1990PubMedCrossRefGoogle Scholar
  11. Piccirillo JF. Inclusion of comorbidity in a staging system for head and neck cancer. Oncology 9:831–836, 1995PubMedGoogle Scholar
  12. Rozack MS, Maipang T, Sabo K, et al: Management of advanced glottic carcinomas. Am J Surg 158:318–320, 1989CrossRefGoogle Scholar
  13. Singh B, Alfonso A, Sabin S, et al: Outcome differences in younger and older patients with laryngeal cancer: a retrospective case-control study. Am J Otolaryngol 21:92–97, 2000PubMedCrossRefGoogle Scholar
  14. Singh B, Bhaya M, Zimbler M, et al: Impact of comorbidity on outcome of young patients with head and neck squamous cell carcinoma. Head Neck 20:1–7, 1998PubMedCrossRefGoogle Scholar
  15. Strong EW. Cancer of the larynx and hypopharynx. Prob Gen Surg 5:166–189, 1988Google Scholar
  16. Van Nostrand AWP, Brodarec I: Laryngeal carcinoma: modification of surgical techniques based upon an understanding of tumor growth characteristics. J Otolaryngol 11:186–192, 1982PubMedGoogle Scholar
  17. Veterans Administration Laryngeal Study Group: Induction chemotherapy plus radiation compared to surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 324:1685–1690, 1991CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • American Joint Committee on Cancer
    • 1
  1. 1.Executive OfficeChicagoUSA

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