Tumors metastatic to the pleura and lung tumors that have extended to the pleural surfaces are not included
Summary of Changes
The AJCC has adopted the staging system proposed by the International Mesothelioma Interest Group (IMIG) in 1995. It is based on updated information about the relationships between tumor T and N status and overall survival. This staging system applies only to tumors arising in the pleura.
T categories have been redefined.
T1 lesions have been divided into T1a and T1b, leading to the division of Stage I into Stage IA and Stage IB.
T3 is defined as locally advanced but potentially resectable tumor.
T4 is defined as locally advanced, technically unresectable tumor.
Stage II no longer involves tumors with nodal metastasis; all nodal metastasis is categorized in Stage III or Stage IV.
KeywordsMalignant Pleural Mesothelioma Malignant Mesothelioma Asbestos Exposure Extrapleural Pneumonectomy Pericardial Mesothelioma
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Allen KB, Faber LP, Warren WH: Malignant pleural mesothelioma: extrapleural pneumonectomy and pleurectomy. Chest Surg Clin N Amer 4:113–126, 1994Google Scholar
Boutin C, Rey F, Gouvernet J, Viallat J-R, Astoul P, Ledoray V: Thoracoscopy in pleural malignant mesothelioma: a prospective study of 188 consecutive patients. Part 2: Prognosis and staging. Cancer 72:394–404, 1993PubMedCrossRefGoogle Scholar
Butchart EG, Ashcroft T, Barnsley WC, Holden MP: Pleuro-pneumonectomy in the management of diffuse malignant mesothelioma of the pleura: experience with 29 patients. Thorax 31:15–24, 1976PubMedCrossRefGoogle Scholar
Pass HI, Temeck BK, Kranda K, Steinberg SM, Feuerstein IR: Preoperative tumor volume is associated with outcome in malignant pleural mesothelioma. J Thorac Cardiovasc Surg 115:310–318, 1998PubMedCrossRefGoogle Scholar
Pass HI, Temeck BK, Kranda K, et al: Phase III randomized trial of surgery with or without intraoperative photodynamic therapy and postoperative immunochemotherapy for malignant pleural mesothelioma. Ann Surg Oncol 4:628–633, 1997PubMedCrossRefGoogle Scholar
Patz EF Jr., Rusch VW, Heelan R: The proposed new international TNM staging system for malignant pleural mesothelioma: application to imaging. Am J Roentgenol 166:323–327, 1996CrossRefGoogle Scholar
Ruffle P, Feld R, Minkin S, et al: Diffuse malignant mesothelioma of the pleura in Ontario and Quebec: a retrospective I study of 332 patients. J Clin Oncol 7:1157–1168, 1989Google Scholar
Rusch VW, The International Mesothelioma Interest Group: A I proposed new international TNM staging system for malignant pleural mesothelioma. Chest 108:1122–1128, 1995PubMedCrossRefGoogle Scholar
Rusch VW, Piantadosi S, Holmes EC: The role of extrapleural pneumonectomy in malignant pleural mesothelioma. J Thorac Cardiovasc Surg 102(l):l-9, 1991Google Scholar
Rusch VW, Venkatraman ES: The importance of surgical staging in the treatment of malignant pleural mesothelioma. J Thorac Cardiovasc Surg 111:815–826, 1996PubMedCrossRefGoogle Scholar
Rusch VW, Venkatraman ES: Important prognostic factors in patients with malignant pleural mesothelioma, managed surgically. Ann Thorac Surg 68:1799–1804, 1999PubMedCrossRefGoogle Scholar
Sugarbaker DJ, Flores RM, Jaklitsch MT, et al: Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results of 183 patients. J Thorac Cardiovasc Surg 117:54–65, 1999PubMedCrossRefGoogle Scholar
Sugarbaker DJ, Strauss GM, Lynch TJ, et al: Node status has prognostic significance in the multimodality therapy of diffuse, malignant mesothelioma. J Clin Oncol 11(6): 1172–1178, 1993PubMedGoogle Scholar
Tammilehto L, Kivisaari L, Salminen US, Maasilta P, Mattson K: Evaluation of the clinical TNM staging system for malignant pleural mesothelioma: an assessment in 88 patients. Lung Cancer 12:25–34, 1995PubMedCrossRefGoogle Scholar
© Springer Science+Business Media New York 2002