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Ampulla of Vater

Carcinoid tumors and other neuroendocrine tumors are not included

  • Chapter
AJCC Cancer Staging Manual

Summary of Changes

There is no longer a distinction between T3 and T4 on the basis of the depth of pancreatic invasion.

The stage grouping has been revised.

Stage I has been replaced with Stage IA and Stage IB.

Stage II has been replaced with Stage IIA and Stage IIB.

Node positive disease has been moved to Stage IIB to retain consistency with the staging of tumors of the bile duct and of the pancreas.

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Bibliography

  • Allema JH, Reinders ME, van Gulik TM, et al: Prognostic factors for survival after pancreaticoduodenectomy for patients with carcinoma of the pancreatic head region. Cancer 75:2069–2076, 1995

    Article  PubMed  CAS  Google Scholar 

  • Bakkevold KE, Kambestad B: Long-term survival following radical and palliative treatment of patients with carcinoma of the pancreas and papilla of Vater—the prognostic factors influencing the long-term results: a prospective multicentre study. Eur J Surg Oncol 19:147–161, 1993

    PubMed  CAS  Google Scholar 

  • Bakkevold KE, Kambestad B: Staging of carcinoma of the pancreas and ampulla of Vater: tumor (T), lymph node (N), and distant metastasis (M) as prognostic factors. Int J Pan-creatol 17:249–259, 1995

    CAS  Google Scholar 

  • Beger HG, Treitschke F, Gansauge F, et al: Tumor of the ampulla of Vater. Arch Surg 134:526–532, 1999

    Article  PubMed  CAS  Google Scholar 

  • Bottger TC, Boddin J, Heintz A, et al: Clinicopathologic study for the assessment of resection for ampullary carcinoma. World J Surg 21:379–383, 1997

    Article  PubMed  CAS  Google Scholar 

  • Compton CC: Protocol for the examination of specimens from patients with carcinoma of the ampulla of Vater. Arch Pathol Lab Med. 121:673–677, 1997

    PubMed  CAS  Google Scholar 

  • Cubilla AL, Fitzgerald PJ: Tumors of the exocrine pancreas. In Atlas of tumor pathology, 2nd series, fascicle 19, Washington, DC: Armed Forces Institute of Pathology, 1984

    Google Scholar 

  • Delcore R Jr, Connor CS, Thomas JH, et al: Significance of tumor spread in adenocarcinoma of the ampulla of Vater. Am J Surg 158:593–596, 1989

    Article  PubMed  Google Scholar 

  • Dorandeau A, Raoul J-L, Sisiser F, Leclercq-Rioux N, et al: Carcinoma of the ampulla of Vater: prognostic factors after curative surgery: a series of 45 cases. Gut 40:350–355, 1997

    Google Scholar 

  • Griffanti-Bartoli F, Arnone GB, Ceppa P, et al: Malignant tumors in the head of the pancreas and the periampullary region: diagnostic and prognostic aspects. Anticancer Res 14:657–666, 1994

    PubMed  CAS  Google Scholar 

  • Harada N, Treitschke F, Imaizumi T, Beger HG. Pancreatic invasion is a prognostic indicator after radical resection for carcinoma of the ampulla of Vater. J Hep Bil Pancr Surg 4:215–219, 1997

    Article  Google Scholar 

  • Howe JR, Klimstra DS, Moccia RD, et al: Factors predictive of survival in ampullary carcinoma. Ann Surg 228:87–94, 1998

    Article  PubMed  CAS  Google Scholar 

  • Kayahara M, Nagakawa T, Ohta T, Kitagawa H, Miyazaki I. Surgical strategy for carcinoma of the papilla of Vater on the basis of lymphatic spread and mode of recurrence. Surgery 121:611–617, 1997

    Article  PubMed  CAS  Google Scholar 

  • Klempnauer J, Ridder GH, Bektas H, et al: Surgery for exocrine pancreatic cancer—who are the 5- and 10-year survivors? Oncology 52:353–359, 1995

    Article  PubMed  CAS  Google Scholar 

  • Knox RA, Kingston RD: Carcinoma of the ampulla of Vater. Br J Surg 73:72–73, 1976

    Article  Google Scholar 

  • Lee JH, Whittington R, Williams NN, et al: Outcome of pancreaticoduodenectomy and impact of adjuvant therapy for ampullary carcinomas. Int J Radiat Oncol Biol Phys 47:945–953, 2000

    Article  PubMed  CAS  Google Scholar 

  • Makipour H, Cooperman A, Danzi JT, et al: Carcinoma of the ampulla of Vater. Ann Surg 183:341–344, 1976

    Article  PubMed  CAS  Google Scholar 

  • Martin MF, Rossi RL, Dorucci V, et al: Clinical and pathologic correlations in patients with periampullary tumors. Arch Surg 125:723–726, 1990

    Article  PubMed  CAS  Google Scholar 

  • Monson JRT, Donohue JH, McEntee GP, et al: Radical resection for carcinoma of the ampulla of Vater. Arch Surg 126:353 – 357, 1991

    Google Scholar 

  • Mori K, Ikei S, Yamane T, et al: Pathological factors influencing survival of carcinoma of the ampulla of Vater. Eur J Surg Oncol 16:183–188, 1990

    PubMed  CAS  Google Scholar 

  • Nelptolemos JP, Talbot IC, Shaw DC, et al: Long-term survival after resection of ampullary carcinoma is associated independently with tumor grade and a new staging classification that assesses local invasiveness. Cancer 61:1403–1407, 1988

    Article  Google Scholar 

  • Roberts RH, Krige JE, Bornman PC, Terblanche J. Pancreaticoduodenectomy of ampullary carcinoma. Am Surg 65:1043–1048, 1999

    PubMed  CAS  Google Scholar 

  • Shirai Y, Tsukada K, Ohtani T, et al: Carcinoma of the ampulla of Vater: histopathologic analysis of tumor spread in Whipple pancreatoduodenectomy specimens. World J Surg 19:102–107, 1995

    Article  PubMed  CAS  Google Scholar 

  • Talamini MA, Moesinger RC, Pitt HA, et al: Adenocarcinoma of the ampulla of Vater: a 28-year experience. Ann Surg 225:590–600, 1997

    Article  PubMed  CAS  Google Scholar 

  • Willett CG, Warshaw AL, Convery K, et al: Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. Surg Gynecol Obstet 176:33–38, 1993

    PubMed  CAS  Google Scholar 

  • Wise L, Pizzimbono C, Dehner IP: Periampullary cancer. Am J Surg 131:141–148, 1976

    Article  PubMed  CAS  Google Scholar 

  • Yamaguchi K, Enjoji M: Carcinoma of the ampulla of Vater: a clinicopathologic study and pathologic staging of 109 cases of carcinoma and 5 cases of adenoma. Cancer 59:506–515, 1987

    Article  PubMed  CAS  Google Scholar 

  • Yasuda K, Mukai H, Cho E, et al: The use of endoscopic ultrasonography in the diagnosis and staging of carcinoma of the papilla of Vater. Endoscopy 20(Suppl):218–222, 1988

    Article  PubMed  Google Scholar 

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Authors and Affiliations

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    American Joint Committee on Cancer

    Editor information

    Editors and Affiliations

    1. Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA

      Frederick L. Greene M.D. (Chair) (Chair)

    2. Vanderbilt University Medical Center, Nashville, Tennessee, USA

      David L. Page M.D. (Professor of Pathology and Epidemiology) (Professor of Pathology and Epidemiology)

    3. Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA

      Irvin D. Fleming M.D. (Professor) (Professor)

    4. Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA

      April G. Fritz C.T.R., R.H.I.T.

    5. The Johns Hopkins School of Medicine, Baltimore, Maryland, USA

      Charles M. Balch M.D. (Professor of Surgery and Oncology) (Professor of Surgery and Oncology)

    6. University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA

      Daniel G. Haller M.D. (Professor of Medicine, Associate Chief for Clinical Affairs) (Professor of Medicine, Associate Chief for Clinical Affairs)

    7. Lynn Sage Breast Center, School of Medicine, Northwestern University, Chicago, Illinois, USA

      Monica Morrow M.D. (Professor of Surgery and Director) (Professor of Surgery and Director)

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    © 2002 Springer Science+Business Media New York

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    American Joint Committee on Cancer. (2002). Ampulla of Vater. In: Greene, F.L., et al. AJCC Cancer Staging Manual. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3656-4_17

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    • DOI: https://doi.org/10.1007/978-1-4757-3656-4_17

    • Publisher Name: Springer, New York, NY

    • Print ISBN: 978-3-540-00595-7

    • Online ISBN: 978-1-4757-3656-4

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