Anal Canal

The classification applies to carcinomas only; melanomas, carcinoid tumors, and sarcomas are not included
  • American Joint Committee on Cancer

Summary of Changes

The definition of TNM and the Stage Grouping for this chapter have not changed from the Fifth Edition.


Anal Canal Dentate Line Mucinous Adenocarcinoma Verrucous Carcinoma Anal Margin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Boman BM, Moertel CG, O’Connell MJ, et al: Carcinoma of the anal canal: a clinical and pathologic study of 188 cases. Cancer 54:114–125, 1984PubMedCrossRefGoogle Scholar
  2. Cummings BJ: Anal canal carcinoma. In Hermanek P, Gospodarowicz MK, Henson DE, et al (Eds.): Prognostic factors in cancer. Berlin: Springer-Verlag, 1995Google Scholar
  3. Dean GT, McAleer JJA, Spence RAJ: Malignant anal tumors. Br J Surg 81:500–508, 1994CrossRefGoogle Scholar
  4. Fenger C, Frisch M, Marti MC, Parc R: Tumors of the anal canal. In Hamilton SR, Aaltonen LA (Eds): World Health Organization classification of tumors: pathology and genetics of tumors of the digestive system. Lyon: IARC Press, 146,2000Google Scholar
  5. Flam MS, John M, Lovalvo LJ, et al: Definitive nonsurgical therapy of epithelial malignancies of the anal canal. Cancer 51:1378–1387, 1983PubMedCrossRefGoogle Scholar
  6. Longo WE, Vernava AM III, Wade TP, et al: Recurrent squamous cell carcinoma of the anal canal: predictors of initial treatment failure and results of salvage therapy. Ann Surg 220:40–49, 1994PubMedCrossRefGoogle Scholar
  7. Nigro ND: An evaluation of combined therapy for squamous cell cancer of the anal canal. Dis Colon Rectum 27:763–766, 1984PubMedCrossRefGoogle Scholar
  8. Nigro ND, Vaitkeviceus VK, Herskovic AM: Preservation of function in the treatment of cancer of the anus. Important Adv Oncol 161–177, 1989Google Scholar
  9. Paradis P, Douglass HO Jr, Holyoke ED: The clinical implications of a staging system for carcinoma of the anus. Surg Gynecol Obstet 141:411–416, 1975PubMedGoogle Scholar
  10. Pintor MP, Northover JM, Nicholls RJ: Squamous cell carcinoma of the anus at one hospital from 1948. Br J Surg 76:806–810, 1989PubMedCrossRefGoogle Scholar
  11. Roseau G, Palazzo L, Colardelle P, et al: Endoscopic ultrasonography in the staging and follow-up of epidermoid carcinoma of the anal canal. Gastrointest Endosc 40:447–450, 1994PubMedCrossRefGoogle Scholar
  12. Ryan DP, Compton CC, Mayer RJ: Carcinoma of the anal canal. NEJM 342(11):792–800, 2000PubMedCrossRefGoogle Scholar
  13. Shepherd NA, Scholefield JH, Love SB, et al: Prognostic factors in anal squamous carcinoma: a multivariate analysis of clinical, pathological and flow cytometric parameters in 235 cases. Histopathology 16:545–555, 1990PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • American Joint Committee on Cancer
    • 1
  1. 1.Executive OfficeChicagoUSA

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