Some Aspects of Analysis of Gene Array Data

  • Borko D. Jovanovic
  • Raymond C. Bergan
  • Warren A. Kibbe
Part of the Cancer Treatment and Research book series (CTAR, volume 113)


The past century brought along tremendous development in statistical methods, accompanying similar advances in the biomedical field and genetics (Elston and Thompson, 2000). In the later half of 1990’s another significant leap forward has occurred in the biomedical field with the advent of gene arrays (Duggan et al., 1999). Gene arrays provide the ability to measure the presence of tens of thousands of genes at one time, and to compare this set of genes between two or more systems. The emergence of this technology, along with attempts to integrate data output with underlying biology, has created one of most lively areas of applied multivariate statistics to recently emerge.


Acute Myeloid Leukemia Microarray Data Housekeeping Gene Singular Value Decomposition Gene Array 
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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Borko D. Jovanovic
    • 1
    • 3
    • 4
  • Raymond C. Bergan
    • 2
    • 3
  • Warren A. Kibbe
    • 3
  1. 1.Department of Preventive MedicineNorthwestern UniversityUSA
  2. 2.Division of Hematology/Oncology, Department of MedicineNorthwestern UniversityUSA
  3. 3.Robert H. Lurie Comprehensive CancerNorthwestern UniversityUSA
  4. 4.General Clinical Research Center of The Feinberg School of MedicineNorthwestern UniversityUSA

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