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Dopaminergic Effects on Acquisition and Consolidation: A Microdialysis Study

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Book cover Catecholamine Research

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 53))

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Abstract

While experimental animals are learning on a schedule-controlled discrimination learning task in an operant type Skinner box, one may examine the relationship between learning ability and neurochemical changes by measuring the content of various neurotransmitters using a microdialysis method. In particular, some of the catecholamines have much closer correlations with learning ability compared to other neurotransmitters. Among the catecholamines, dopamine and its metabolites in amygdala, hippocampus, thalamus, and cortex are increased during learning performance. Dopamine appears to play an important role in the acquisition and consolidation stages of learning.

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© 2002 Springer Science+Business Media New York

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Nomura, M., Maruki, K., Hori, K. (2002). Dopaminergic Effects on Acquisition and Consolidation: A Microdialysis Study. In: Nagatsu, T., Nabeshima, T., McCarty, R., Goldstein, D.S. (eds) Catecholamine Research. Advances in Behavioral Biology, vol 53. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-3538-3_82

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  • DOI: https://doi.org/10.1007/978-1-4757-3538-3_82

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-3388-1

  • Online ISBN: 978-1-4757-3538-3

  • eBook Packages: Springer Book Archive

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