Abstract
Two main types of methods are available for the “in vivo” monitoring of catecholamines (CA) in the brain (review in Kehr, 1999): i) “in vivo” electrochemistry, improperly often referred to as “in vivo” voltammetry, which belongs to the “in situ” methods since they rely on a carbon fiber microlectrode measuring directly the CA within the cerebral tissue and ii) “in vivo” microdialysis technique, which belongs to the “ex situ” methods since it requires the collection of a dialysate which is then analyzed with one or several of the suitable techniques, e.g. HPLC with electrochemical detection for CA.
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Bert, L., Martin, V., Lambas-Señas, L., Suaud-Chagny, MF., Renaud, B. (2002). Determination of Subnanomolar Concentrations of Dopamine and Norepinephrine in Nanovolume Samples Using an Automated Capillary Zone Electrophoresis with Laser Induced Fluorescence Detection. In: Nagatsu, T., Nabeshima, T., McCarty, R., Goldstein, D.S. (eds) Catecholamine Research. Advances in Behavioral Biology, vol 53. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-3538-3_73
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DOI: https://doi.org/10.1007/978-1-4757-3538-3_73
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