Regulation of Cell Death by the Bcl-2 Family of Proteins
One of the promising approaches for the treatment or prevention of neurodegenerative diseases, including Parkinson’s disease, is to investigate the molecular basis of neurodegeneration or neuronal death and elucidate possible therapeutic molecular targets. The Bcl-2 family of proteins is a major cell death regulator and is implicated in determining the survival or death of neurons under physiological as well as pathological conditions. I will provide an overview of the functions of this family of proteins and their targets, and will discuss a possible molecular approach for the prevention of neurodegenerative diseases.
KeywordsSpinal Muscular Atrophy Necrotic Cell Death Spinal Muscular Atrophy Patient Necrotic Death Therapeutic Molecular Target
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Refernces (our works cited)
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