Chromogranins / Current Concept

  • Dominique Aunis
  • Marie-Hélène Metz-Boutigue
Part of the Advances in Behavioral Biology book series (ABBI, volume 53)


The large dense core secretory granules of adrenal medulla chromaffin cells synthesize, store and release catecholamines. Upon cell stimulation intragranular stored material is liberated into circulation to activate target organs. In addition to catecholamines, numerous peptides and proteins are present in chromaffin secretory granules and are exocytotically co-secreted with the catecholamines (Aunis, 1997).


Microglial Cell Secretory Granule Chromaffin Cell Dystrophic Neurites Chromaffin Granule 
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© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Dominique Aunis
  • Marie-Hélène Metz-Boutigue
    • 1
  1. 1.Unité Inserm U.338Centre de NeurochimieStrasbourg CedexFrance

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