Dopamine Transporter and Parkinson’s Disease
Dopaminergic transmission is terminated by the rapid reuptake of dopamine into presynaptic nerve terminals via a dopamine transporter (DAT) localized in presynaptic cytoplasmic membranes. Since Parkinson’s disease (PD) is closely related with dopamine metabolism, we investigated the relationship between DAT and PD to develop a new therpeutic approach to the disease.
KeywordsPC12 Cell Nerve Growth Factor Nicotinic Receptor Dopamine Transporter Dopamine Uptake
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