Basic Ideas of Mathematical Epidemiology
The idea of invisible living creatures as agents of disease goes back at least to the writings of Aristotle (384 BC-322 BC). It developed as a theory in the 16th century. The existence of microorganisms was demonstrated by Leeuwenhoek (1632–1723) with the aid of the first microscopes. The first expression of the germ theory of disease by Jacob Henle (1809–1885) came in 1840 and was developed by Robert Koch (1843–1910), Joseph Lister (1827–1912), and Louis Pasteur (1827–1875) in the latter part of the 19th century and the early part of the 20th century.
KeywordsEndemic Equilibrium Total Population Size Infective Period Basic Reproductive Number Proportional Death Rate
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