Peptide Receptor Imaging

  • Franklin C. L. Wong
  • E. Edmund Kim

Abstract

Peptides are small number (<50) of units of amino acids covalently linked by the peptide bond. They are smaller in size and lower in molecular weight (<10,000 daltons) than proteins. Peptides also lack tertiary structures. Therefore, they are less prone to immunogenicity. Because target-specific imaging using monoclonal antibodies has proven elusive, imaging using biologically active peptides has raised enthusiasm among scientists and clinicians. This interest is because of the wealth of molecular recognition technology and protein biochemistry that may be applied to the diagnosis of human disease by direct visualization of the specific disease sites. This technology has become possible with the recent advances in imaging devices, protein chemistry, and the understanding of the physiological and pathological roles of protein and peptides.

Keywords

Positron Emission Tomography Vasoactive Intestinal Peptide Receptor Imaging Solitary Pulmonary Nodule Molecular Recognition Technology 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Franklin C. L. Wong
  • E. Edmund Kim

There are no affiliations available

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